Comparison of OMERACT-RAMRIS scores and computer-aided dynamic magnetic resonance imaging findings of hand and wrist as a measure of activity in rheumatoid arthritis

dc.contributor.authorOrguc S.
dc.contributor.authorTikiz C.
dc.contributor.authorAslanalp Z.
dc.contributor.authorErbay P.D.
dc.date.accessioned2024-07-22T08:18:06Z
dc.date.available2024-07-22T08:18:06Z
dc.date.issued2013
dc.description.abstractThe purpose of this study was to compare the value of conventional magnetic resonance imaging (MRI) finding of rheumatoid arthritis (RA) and computer-aided dynamic MRI measurements in predicting the activity of disease. The activity of the disease in 40 RA patients was evaluated by the disease activity score in 28 joints (DAS28). The conventional MRI of the wrists of all patients were scored for bone edema, synovitis and erosions, according to the criteria of RA-MRI scoring system (RAMRIS) developed by Outcome measures in rheumatology clinical trials (OMERACT) MR Imaging Group. Synovitis was also quantified by dynamic postcontrast MRI imaging using color coded maximum slope of increase maps and measurements of early enhancement rate (EER) and relative enhancement (RE). Twenty-two (55 %) patients with a score higher than 5.1 constituted the high disease activity group, 18 (45 %) patients with a score of 5.1 or less constituted moderate disease activity group. The dynamic MRI-EER score was the most significant parameter to differentiate between the groups (p = 0.001). Among OMERACT scores, only bone edema [p = 0.020 for wrist and p = 0.037 for metacarpophalangeal joints (MCP)] had a significant difference between the two groups. Dynamic MRI RE score and OMERACT scores for erosions and synovitis for both the wrist and MCP joints did not differ significantly between the two groups. Computer-aided dynamic MRI is a reliable, noninvasive method of evaluating the RA patients, which correlates with the DAS28 scores, at a higher significance than the OMERACT-RAMRIS scores. © 2013 Springer-Verlag Berlin Heidelberg.
dc.identifier.DOI-ID10.1007/s00296-012-2658-z
dc.identifier.issn1437160X
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/17191
dc.language.isoEnglish
dc.subjectAdult
dc.subjectAged
dc.subjectArthritis, Rheumatoid
dc.subjectContrast Media
dc.subjectEdema
dc.subjectFemale
dc.subjectHand Joints
dc.subjectHumans
dc.subjectImage Interpretation, Computer-Assisted
dc.subjectMagnetic Resonance Imaging
dc.subjectMale
dc.subjectMiddle Aged
dc.subjectPredictive Value of Tests
dc.subjectSeverity of Illness Index
dc.subjectSynovitis
dc.subjectWrist Joint
dc.subjectYoung Adult
dc.subjectgadolinium pentetate
dc.subjectadult
dc.subjectaged
dc.subjectarticle
dc.subjectbone erosion
dc.subjectclinical article
dc.subjectcomputer assisted diagnosis
dc.subjectcontrast enhancement
dc.subjectdisease activity
dc.subjectdisease activity score
dc.subjectedema
dc.subjectfemale
dc.subjecthand
dc.subjecthuman
dc.subjectintermethod comparison
dc.subjectmale
dc.subjectmetacarpophalangeal joint
dc.subjectnuclear magnetic resonance imaging
dc.subjectnuclear magnetic resonance scanner
dc.subjectOMERACT RAMRIS score
dc.subjectpriority journal
dc.subjectprognosis
dc.subjectrheumatoid arthritis
dc.subjectscoring system
dc.subjectsynovitis
dc.subjectwrist
dc.titleComparison of OMERACT-RAMRIS scores and computer-aided dynamic magnetic resonance imaging findings of hand and wrist as a measure of activity in rheumatoid arthritis
dc.typeArticle

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