Mechanisms and grading of nocturia: Results from a multicentre prospective study

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dc.contributor.authorBozkurt O.
dc.contributor.authorIrer B.
dc.contributor.authorKizilay F.
dc.contributor.authorErbatu O.
dc.contributor.authorSen V.
dc.contributor.authorCinar O.
dc.contributor.authorOngun S.
dc.contributor.authorCihan A.
dc.contributor.authorOzdemir T.
dc.contributor.authorTasdemir D.
dc.contributor.authorUcer O.
dc.date.accessioned2024-07-22T08:06:11Z
dc.date.available2024-07-22T08:06:11Z
dc.date.issued2021
dc.description.abstractObjective: To identify the pathophysiological mechanisms of nocturia and the correlation of these mechanisms with nocturia severity. Methodology: After approval by the local ethics committee, all patients with nocturia (≥1 nocturnal void/night) were included and filled the Overactive Bladder questionnaire, Nocturia Quality of Life, Incontinence Questionnaire - Male Lower Urinary Tract Symptoms (male), International Consultation on Incontinence Questionnaire - Female Lower Urinary Tract Symptoms (female) and 3-day frequency-volume chart. Patients were divided into three groups according to the severity of nocturia: group 1 consisted of patients with mild (1-2 voids/night), group 2 with moderate (3-4 voids/night) and group 3 with severe nocturia (>4 voids/night). Comparative analysis was performed between groups, and P <.05 was deemed as statistically significant. Results: About 68.1%, 64.1% and 8.7% of the patients had nocturnal polyuria (NP), reduced bladder capacity and global polyuria, respectively. 42.7% of the patients had mixed nocturia. 6.1% of the patients did not comply with the aforementioned subtypes and defined as isolated nocturia. Regarding the severity of nocturia, 155 (41%) patients had mild, 167 (45%) patients had moderate and 57 (15%) patients had severe nocturia. Increased nocturia severity was related with decreased quality of life; higher age, urinary tract symptom scores, nocturnal urine volume, evening fluid consumption and beta-blocker medication rates. Increased nocturia severity was also associated with higher NP, global polyuria and reduced bladder capacity rates. Conclusions: Nocturia mechanisms may vary between mild and moderate to severe nocturia groups according to the present study. Nocturia grading with identification of subtypes may help for better standardisation of the diagnostic and treatment approaches as well as for the design of future clinical trials. © 2020 John Wiley & Sons Ltd
dc.identifier.DOI-ID10.1111/ijcp.13722
dc.identifier.issn13685031
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/13408
dc.language.isoEnglish
dc.publisherJohn Wiley and Sons Inc
dc.rightsAll Open Access; Gold Open Access
dc.subjectFemale
dc.subjectHumans
dc.subjectMale
dc.subjectNocturia
dc.subjectPolyuria
dc.subjectProspective Studies
dc.subjectQuality of Life
dc.subjectUrinary Bladder, Overactive
dc.subjectadult
dc.subjectaged
dc.subjectArticle
dc.subjectbladder capacity
dc.subjectbody mass
dc.subjectcomorbidity
dc.subjectcontrolled study
dc.subjectdemography
dc.subjectdisease association
dc.subjectdisease severity
dc.subjectfemale
dc.subjectglobal polyuria
dc.subjecthuman
dc.subjectICIQ (incontinence)
dc.subjectInternational Consultation on Incontinence Questionnaire Male Lower Urinary Tract Symptoms
dc.subjectmajor clinical study
dc.subjectmale
dc.subjectmixed nocturia
dc.subjectnocturia
dc.subjectNocturia Quality of Life Questionnaire
dc.subjectnocturnal polyuria
dc.subjectOveractive Bladder questionnaire
dc.subjectpolyuria
dc.subjectpost hoc analysis
dc.subjectprospective study
dc.subjectquality of life
dc.subjectquestionnaire
dc.subjectscoring system
dc.subjecturine volume
dc.subjecturoflowmetry
dc.subjectclinical trial
dc.subjectcomplication
dc.subjectmulticenter study
dc.subjectnocturia
dc.subjectoveractive bladder
dc.subjectpolyuria
dc.titleMechanisms and grading of nocturia: Results from a multicentre prospective study
dc.typeArticle

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