Efficacy of terbinafine 1% cream on seborrhoeic dermatitis

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dc.contributor.authorGündüz K.
dc.contributor.authorInanir I.
dc.contributor.authorSacar H.
dc.date.accessioned2024-07-22T08:24:05Z
dc.date.available2024-07-22T08:24:05Z
dc.date.issued2005
dc.description.abstractSeborrhoeic dermatitis (SD) is a common chronic inflammatory skin disease. Although the exact pathogenesis of SD is unknown, Malassezia yeasts as well as genetic and environmental factors have been implicated. The aim of this study was to evaluate the efficacy of terbinafine 1% cream on SD lesions with face localisation. Thirty-five patients with SD were included in the study. Patients applied terbinafine 1% cream twice daily for four weeks. The severity of the signs (erythema, scaling, infiltration) was assessed using a 4-point score (0=absent, 1=mild, 2=moderate, and 3=intense) at baseline and at the 2nd and 4th weeks of the therapy. Also, self-assessment was done by the patients on a 100 mm visual analogue score (VAS) at each visit. Complete remission was observed in 10 (32.3%) patients at the end of the therapy. Statistically significant reductions in the scores of all parameters were observed at both the 2nd and 4th weeks of the therapy. Patients' self assessments in the 2nd and 4th weeks were similarly better than at the baseline.
dc.identifier.DOI-ID10.1111/j.1346-8138.2005.tb00708.x
dc.identifier.issn03852407
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/19823
dc.language.isoEnglish
dc.publisherJapanese Dermatological Association
dc.subjectantifungal agent
dc.subjectterbinafine
dc.subjectadolescent
dc.subjectadult
dc.subjectaged
dc.subjectarticle
dc.subjectcell infiltration
dc.subjectclinical article
dc.subjectdisease severity
dc.subjectdrug efficacy
dc.subjectdrug safety
dc.subjecterythema
dc.subjectfemale
dc.subjecthuman
dc.subjectMalassezia
dc.subjectmale
dc.subjectremission
dc.subjectscoring system
dc.subjectseborrheic dermatitis
dc.subjectside effect
dc.subjectskin manifestation
dc.subjectstatistical analysis
dc.subjectvisual analog scale
dc.titleEfficacy of terbinafine 1% cream on seborrhoeic dermatitis
dc.typeArticle

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