Evaluation of patients with zygomycosis

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dc.contributor.authorKaya O.
dc.contributor.authorAlp Çavuş S.
dc.contributor.authorTurhan Ö.
dc.contributor.authorIşikgöz Taşbakan M.
dc.contributor.authorPullukçu H.
dc.contributor.authorErtuǧrul M.B.
dc.contributor.authorŞenol Ş.
dc.contributor.authorÇetin Ç.B.
dc.contributor.authorÖzhak Baysan B.
dc.contributor.authorSayin Kutlu S.
dc.contributor.authorMetin D.Y.
dc.contributor.authorAvci M.
dc.contributor.authorMermut G.
dc.contributor.authorAvkan Oǧuz V.
dc.contributor.authorYapar N.
dc.date.accessioned2024-07-22T08:17:16Z
dc.date.available2024-07-22T08:17:16Z
dc.date.issued2014
dc.description.abstractAim: Zygomycosis is a severe angioinvasive infection caused by Zygomycetes. We retrospectively investigated 16 cases of zygomycosis. Materials and methods: The data of patients, who had been followed between 2004 and 2010 in 8 tertiary-care teaching hospitals, were reviewed. Demographic characteristics, underlying diseases, and clinical signs and symptoms of the patients, as well as diagnostic methods, data obtained by radiological imaging methods, and the therapies, were recorded. Therapeutic approaches, antifungal agents and duration of use, and the characteristics of the cases were identified. Results: The study included 11 female and 5 male subjects. The most common symptoms and clinical signs were fever (n = 9) and retro-orbital pain (n = 7). Rhinocerebral zygomycosis was the most common form. The mean time elapsed for diagnosis was 14.26 ± 13.96 (range: 2-52) days. Antifungal therapy was given to 15 patients (94%). In addition to antifungal therapy, 12 patients underwent surgical intervention 1 to 4 times. The mean duration of receiving antifungal therapy was 61.4 ± 58.02 (range: 1-180) days. The median duration of treatment was 62.5 (range: 42-180) days in survivors. Conclusion: Zygomycosis is an infectious disease with high mortality despite antifungal therapy and surgical interventions. © TÜBİTAK.
dc.identifier.DOI-ID10.3906/sag-1303-48
dc.identifier.issn13000144
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/17008
dc.language.isoEnglish
dc.publisherTurkiye Klinikleri Journal of Medical Sciences
dc.rightsAll Open Access; Bronze Open Access
dc.subjectAdult
dc.subjectAged
dc.subjectAntifungal Agents
dc.subjectFemale
dc.subjectHumans
dc.subjectMale
dc.subjectMiddle Aged
dc.subjectRetrospective Studies
dc.subjectYoung Adult
dc.subjectZygomycosis
dc.subjectamphotericin B lipid complex
dc.subjectantifungal agent
dc.subjectvoriconazole
dc.subjectadult
dc.subjectaged
dc.subjectarticle
dc.subjectaspergillosis
dc.subjectAspergillus flavus
dc.subjectclinical article
dc.subjectfemale
dc.subjectfever
dc.subjectfungus culture
dc.subjecthistopathology
dc.subjecthuman
dc.subjectmale
dc.subjectmedical record review
dc.subjectMucor
dc.subjectpain
dc.subjectretroorbital pain
dc.subjectrhinocerebral zygomycosis
dc.subjectRhizomucor
dc.subjectRhizopus
dc.subjecttreatment duration
dc.subjectzygomycosis
dc.subjectmiddle aged
dc.subjectretrospective study
dc.subjectyoung adult
dc.subjectzygomycosis
dc.titleEvaluation of patients with zygomycosis
dc.typeArticle

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