Atherogenic profile in preeclampsia

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dc.contributor.authorVar A.
dc.contributor.authorKuşcu N.K.
dc.contributor.authorKoyuncu F.
dc.contributor.authorUyanik B.S.
dc.contributor.authorOnur E.
dc.contributor.authorYildirim Y.
dc.contributor.authorOruç S.
dc.date.accessioned2024-07-22T08:25:02Z
dc.date.available2024-07-22T08:25:02Z
dc.date.issued2003
dc.description.abstractAtherosis is accepted to underlie the pathogenesis of preeclampsia, therefore we aimed to determine malonyldialdehyde (MDA) levels as a marker of lipid peroxidation, and lipoprotein(a) (Lp(a)), apolipoprotein A-1 (Apo A-1) and apolipoprotein B (Apo B) levels as a marker of atherogenic profile in preeclamptic and normal pregnant women. Twenty preeclamptic and 20 gestational-age matched normal pregnant patients were enrolled in the study, mean gestational ages for the preeclamptic and the control group were 33.9±1.4 and 35.5±0.7 weeks, respectively. Blood was withdrawn from the patients soon after diagnosis, and from the controls at their routine prenatal visits. MDA levels was significantly higher in preeclamptic patients (P=0.0003), but no difference was observed in Apo A-1 and Apo B and Lp(a) levels between the 2 groups. We consider that higher MDA was due to oxidative stress seen in preeclampsia, and similar Apo A-1 and Apo B and Lp(a) levels were due to lack of systemic atherosis.
dc.identifier.DOI-ID10.1007/s00404-002-0317-4
dc.identifier.issn09320067
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/20245
dc.language.isoEnglish
dc.publisherSpringer Verlag
dc.subjectapolipoprotein A1
dc.subjectapolipoprotein B
dc.subjectlipoprotein A
dc.subjectmalonaldehyde
dc.subjectadult
dc.subjectarticle
dc.subjectatherogenesis
dc.subjectatherosclerosis
dc.subjectclinical article
dc.subjectcontrolled study
dc.subjectfemale
dc.subjectgestational age
dc.subjecthuman
dc.subjectlipid peroxidation
dc.subjectoxidative stress
dc.subjectpathogenesis
dc.subjectpreeclampsia
dc.subjectprenatal diagnosis
dc.titleAtherogenic profile in preeclampsia
dc.typeArticle

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