Leptin levels in patients with Behçet's disease; [Behçet hastalarinda leptin düzeyleri]

dc.contributor.authorInanir I.
dc.contributor.authorGündüz K.
dc.contributor.authorOnur E.
dc.contributor.authorPirildar T.
dc.contributor.authorVar A.
dc.contributor.authorÖlçer N.
dc.date.accessioned2024-07-22T08:20:39Z
dc.date.available2024-07-22T08:20:39Z
dc.date.issued2010
dc.description.abstractBackground and Design: Leptin is a hormone, which regulates neuroendocrine function and also is involved in inflammatory processes. Proinflammatorycytokines, important inducers in the pathogenesis of Behçet's disease, up-regulate the leptin levels. In this study, we aimed to compare leptin levels in patients with Behcet's disease to those in controls and to investigate the correlation between leptin levels and disease activity. Material and Method: Fifty-three patients with Behçet's disease (28 active and 25 inactive) composed the study group and 22 subjects-the control group . Leptin analyses were done by ELISA method using commercial kits. Erythrocyte sedimentation rate and C-reactive protein levels were also measured. Results: Leptin levels were increased in patients with Behçet's disease compared to controls. Leptin did not correlate with disease activity. Conclusion: Leptin might have a possible role in the pathogenesis of Behcet's disease.
dc.identifier.DOI-ID10.4274/turkderm.44.209
dc.identifier.issn1019214X
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/18264
dc.language.isoTurkish
dc.subjectC reactive protein
dc.subjectleptin
dc.subjectarticle
dc.subjectBehcet disease
dc.subjectcomparative study
dc.subjectcontrolled study
dc.subjectcorrelation analysis
dc.subjectdisease activity
dc.subjectenzyme linked immunosorbent assay
dc.subjecterythrocyte sedimentation rate
dc.subjecthuman
dc.subjectmajor clinical study
dc.subjectprotein analysis
dc.subjectprotein blood level
dc.titleLeptin levels in patients with Behçet's disease; [Behçet hastalarinda leptin düzeyleri]
dc.typeArticle

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