The effect of levosimendan in patients undergoing to coronary bypass operation with low ejection fraction; [Koroner baypas geçi̇ren düşük ejeksi̇yon fraksi̇yonlu hastalarda levosi̇mendanin etki̇leṙi]

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dc.contributor.authorKurdal A.T.
dc.contributor.authorÖztürk T.
dc.contributor.authorBadak O.T.
dc.contributor.authorEserdaǧ M.
dc.contributor.authorIşkesin I.
dc.contributor.authorCerrahoǧlu M.
dc.contributor.authorŞirin B.H.
dc.date.accessioned2024-07-22T08:21:44Z
dc.date.available2024-07-22T08:21:44Z
dc.date.issued2009
dc.description.abstractIn this study we determined the effects of levosimendan on hemodynamic parameters during weaning from cardiopulmonary bypass and in the early postoperative period in patients with low ejection fraction. Charts of 39 patients with an ejection fraction of ≤30% who underwent elective coronary artery bypass surgery were reviewed. Nineteen (Group L) had received a loading dose of levosimendan (6 μg·kg-1) within 10 minutes after removal of the cross clamp, followed by an infusion (0.1 mcg·kg-1·min-1). Control patients (n=20, Group C) did not receive levosimendan. Hemodynamic parameters during the early postoperative period were compared. Cardiac index was significantly higher than baseline in both groups at one and six hours after removal of the cross clamp (p<0.05). Cardiac index was significantly greater, and systemic vascular resistance index and Pulmonar vascular resistance index were significantly lower, in Group L at both one and six hours (p<0.001). In conclusion, the use of levosimendan was associated with more favourable hemodynamic effects in patients with low ejection fraction during weaning from cardiopulmonary bypass and in the early postoperative period after Coronary Artery Bypass Grefting surgery.
dc.identifier.issn13068814
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/18756
dc.language.isoTurkish
dc.subjectlevosimendan
dc.subjectaged
dc.subjectartery clamp
dc.subjectarticle
dc.subjectartificial ventilation
dc.subjectcardiopulmonary bypass
dc.subjectclinical article
dc.subjectcontrolled study
dc.subjectcoronary artery bypass graft
dc.subjectcoronary artery bypass surgery
dc.subjectdrug efficacy
dc.subjectelective surgery
dc.subjectfemale
dc.subjectfollow up
dc.subjectheart ejection fraction
dc.subjectheart index
dc.subjecthemodynamic parameters
dc.subjecthuman
dc.subjectlung vascular resistance
dc.subjectmale
dc.subjectmedical record
dc.subjectpostoperative period
dc.subjectsystemic vascular resistance
dc.titleThe effect of levosimendan in patients undergoing to coronary bypass operation with low ejection fraction; [Koroner baypas geçi̇ren düşük ejeksi̇yon fraksi̇yonlu hastalarda levosi̇mendanin etki̇leṙi]
dc.typeArticle

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