Analysis of the Natural Course of Quiescent Macular Neovascularization with Optical Coherence Tomography Angiography
| dc.contributor.author | Akgun, YD | |
| dc.contributor.author | Kurt, E | |
| dc.contributor.author | Altinisik, M | |
| dc.date.accessioned | 2025-04-10T10:30:30Z | |
| dc.date.available | 2025-04-10T10:30:30Z | |
| dc.description.abstract | Purpose This study investigates the natural progression of quiescent macular neovascularization (qMNV) using optical coherence tomography angiography (OCTA). Methods The study monitored 30 eyes of 28 qMNV patients over a period of at least six months. Best-corrected visual acuity (BCVA), optical coherence tomography (OCT), and OCTA were used to perform qualitative and quantitative analyses, noting any cases of activation during follow-up. Results Among the 30 eyes (14 female, mean age 69.70 +/- 7.63 years), 21 had age-related macular degeneration (AMD) and 9 had pachychoroid neovasculopathy (PNV). The mean follow-up duration was 18.9 months. There were no significant changes in qualitative morphological features, BCVA, or choroidal thickness (p > 0.05). However, there was a statistically significant increase in the areas of MNV and flow (p = 0.043 and p = 0.018, respectively). BCVA and MNV area showed no significant correlation (p = 0.103). Four cases (13.33%) showed activation after an average follow-up period of 27.75 months (6 to 48). Additionally, extrafoveal location was identified as a significant risk factor for exudation (p = 0.033). Conclusion OCTA is a valuable tool for monitoring qMNV and identifying potential predictors of disease activation. The qMNV area may increase over time, even in the absence of activation. Extrafoveal location appears to be a potential risk factor for qMNV activation. | |
| dc.identifier.e-issn | 1724-6016 | |
| dc.identifier.issn | 1120-6721 | |
| dc.identifier.uri | http://hdl.handle.net/20.500.14701/37072 | |
| dc.language.iso | English | |
| dc.title | Analysis of the Natural Course of Quiescent Macular Neovascularization with Optical Coherence Tomography Angiography | |
| dc.type | Article; Early Access |