Antibiotic treatment outcomes in community-acquired pneumonia
| dc.contributor.author | Çilli, A | |
| dc.contributor.author | Sayiner, A | |
| dc.contributor.author | Çelenk, B | |
| dc.contributor.author | Sakar Coskun, A | |
| dc.contributor.author | Kilinç, O | |
| dc.contributor.author | Hazar, A | |
| dc.contributor.author | Aktas Samur, A | |
| dc.contributor.author | Tasbakan, S | |
| dc.contributor.author | Waterer, GW | |
| dc.contributor.author | Havlucu, Y | |
| dc.contributor.author | Kiliç, Ö | |
| dc.contributor.author | Tokgöz, F | |
| dc.contributor.author | Bilge, U | |
| dc.date.accessioned | 2025-04-10T10:36:47Z | |
| dc.date.available | 2025-04-10T10:36:47Z | |
| dc.description.abstract | Background/aim: The optimal empiric antibiotic regimen for patients with community-acquired pneumonia (CAP) remains unclear. This study aimed to evaluate the clinical cure rate, mortality, and length of stay among patients hospitalized with community-acquired pneumonia in nonintensive care unit (ICU) wards and treated with a beta-lactam, beta-lactam and macrolide combination, or a fluoroquinolone. Materials and methods: This prospective cohort study was perfbrined using standardized web-based database sheets from January 2009 to September 2013 in nine tertiary care hospitals in Turkey. Results: Six hundred and twenty-one consecutive patients were enrolled. A pathogen was identified in 78 (12.6%) patients. The most frequently isolated bacteria were S. pneumoniae (21.8%) and P. aeruginosa (19.2%). The clinical cure rate and length of stay were not different among patients treated with beta-lactam, beta-lactam and macrolide combination, and fluoroquinolone. Forty-seven patients (9.2%) died during the hospitalization period. There was no difference in survival among the three treatment groups. Conclusion: In patients admitted to non-ICU hospital wards for CAP, there was no difference in clinical outcomes between beta-lactam, beta-lactam and macrolide combination, and fluoroquinolone regimens. | |
| dc.identifier.e-issn | 1303-6165 | |
| dc.identifier.issn | 1300-0144 | |
| dc.identifier.uri | http://hdl.handle.net/20.500.14701/42578 | |
| dc.language.iso | English | |
| dc.title | Antibiotic treatment outcomes in community-acquired pneumonia | |
| dc.type | Article |