Children with recurrent abdominal pain in Manisa Region, Western Turkey: An evaluation of serological prevalence of Helicobacter Pylori

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dc.contributor.authorKasirga E.
dc.contributor.authorErtan P.
dc.contributor.authorTosun S.
dc.contributor.authorSanhdag T.
dc.contributor.authorTansug N.
dc.contributor.authorOnag A.
dc.date.accessioned2024-07-22T08:24:58Z
dc.date.available2024-07-22T08:24:58Z
dc.date.issued2003
dc.description.abstractObjective- To evaluate the serological prevalence of Helicobacter Pylori infection in asymptomatic and symptomatic children with recurrent abdominal pain. Design- A cohort was used to study the rate of infection by Helicobacter Pylori in children, the prevalence of IgG antibodies to Helicobacter Pylori was determined. Setting- Manisa region, Western Turkey. Materials and Methods- Fifty-five symptomatic (25 boys and 30 girls) and one hundred sixty-four asymptomatic (82 boys and 82 girls) children between 3-15 years of age were tested for anti-Helicobacter pylori IgG. Serum samples collected were tested for IgG antibodies against Helicobacter pylori by enzyme-linked immunosorbent assay using commercial kits. Mean titers >20 U/ml were considered positive for specific IgG antibody. Result- The prevalence of anti-H. pylori IgG antibody was 65.5% in symptomatic and 35.4% in asymptomatic children. The seroprevalence was increased significantly with age in children and recurrent abdominal pain (chi-square = 18.09; p<0.001). There was a significant difference in the appearance rate of IgG antibodies between asymptomatic and symptomatic children (chi-square = 15.22; p<0.001). Conclusion- This study shows that Helicobacter pylori seropositivity is more common in children with recurrent abdominal pain than in asymptomatic children living in Manisa region, Western Turkey.
dc.identifier.issn14683814
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/20204
dc.language.isoEnglish
dc.subjectimmunoglobulin G antibody
dc.subjectabdominal pain
dc.subjectadolescent
dc.subjectanalytical equipment
dc.subjectantibody specificity
dc.subjectantibody titer
dc.subjectarticle
dc.subjectblood sampling
dc.subjectchi square test
dc.subjectchild
dc.subjectchildhood disease
dc.subjectcohort analysis
dc.subjectcontrolled study
dc.subjectenzyme linked immunosorbent assay
dc.subjectfemale
dc.subjectHelicobacter infection
dc.subjectHelicobacter pylori
dc.subjecthuman
dc.subjecthuman tissue
dc.subjectmajor clinical study
dc.subjectmale
dc.subjectrecurrent disease
dc.subjectseroprevalence
dc.subjectstatistical significance
dc.subjectsymptomatology
dc.subjectTurkey (republic)
dc.titleChildren with recurrent abdominal pain in Manisa Region, Western Turkey: An evaluation of serological prevalence of Helicobacter Pylori
dc.typeArticle

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