Evaluation of hemostatic changes using thromboelastography after crystalloid or colloid fluid administration during major orthopedic surgery

Simple item page
dc.contributor.authorTopçu I.
dc.contributor.authorÇivi M.
dc.contributor.authorÖztürk T.
dc.contributor.authorKeleş G.T.
dc.contributor.authorÇoban S.
dc.contributor.authorYentür E.A.
dc.contributor.authorOkçu G.
dc.date.accessioned2024-07-22T08:19:46Z
dc.date.available2024-07-22T08:19:46Z
dc.date.issued2012
dc.description.abstractThe effects of Ringer lactate, 6% hydroxyethyl starch (130/0.4) or 4% succinylated gelatin solutions on perioperative coagulability were measured by thromboelastography (TEG). Seventy-five patients (ASA I-III) who were to undergo major orthopedic procedures performed under epidural anesthesia were included in the study. Patients were randomly divided into three groups of 25 each for the administration of maintenance fluids: group RL (Ringer lactate), group HES (6% hydroxyethyl starch 130/0.4), and group JEL (4% gelofusine solution). Blood samples were obtained during the perioperative period before epidural anesthesia (t1, baseline), at the end of the surgery (t2), and 24 h after the operation (t3). TEG data, reaction time (R), coagulation time (K), angle value (α), and maximum amplitude (MA) were recorded. TEG parameters changed from normal values in all patients. In group RL, R and K times decreased compared to perioperative values while the α angle and MA increased (P < 0.05). In group HES, R and K times increased, however, the α angle and MA decreased (P < 0.05). In group JEL, R time increased (P < 0.05), but K time, α angle and MA did not change significantly. In the present study, RL, 6% HES (130/0.4) and 4% JEL solutions caused changes in the coagulation system of all patients as measured by TEG, but these changes remained within normal limits.
dc.identifier.DOI-ID10.1590/S0100-879X2012007500095
dc.identifier.issn0100879X
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/17840
dc.language.isoEnglish
dc.publisherAssociacao Brasileira de Divulgacao Cientifica
dc.rightsAll Open Access; Gold Open Access; Green Open Access
dc.subjectgelatin succinate
dc.subjecthetastarch
dc.subjectRinger lactate solution
dc.subjectadult
dc.subjectaged
dc.subjectarticle
dc.subjectblood clotting time
dc.subjectcolloid
dc.subjectcomparative study
dc.subjectcrystalloid
dc.subjectepidural anesthesia
dc.subjectfemale
dc.subjectfluid therapy
dc.subjecthemostasis
dc.subjecthuman
dc.subjectintraoperative period
dc.subjectmajor clinical study
dc.subjectmale
dc.subjectorthopedic surgery
dc.subjectpostoperative period
dc.subjectthromboelastography
dc.titleEvaluation of hemostatic changes using thromboelastography after crystalloid or colloid fluid administration during major orthopedic surgery
dc.typeArticle

Files

Collections

Scopus Koleksiyonu