Successful management of imatinib despite alopecia and nail necrosis

Simple item page
dc.contributor.authorErgene U.
dc.contributor.authorOzbalci D.
dc.date.accessioned2024-07-22T08:18:27Z
dc.date.available2024-07-22T08:18:27Z
dc.date.issued2013
dc.description.abstractImatinib mesylate selectively inhibits bcr/abl and other non-specific tyrosine kinases, such as c-kit and platelet derived growth factor (PDGF) receptor and successfully used to treat chronic myeloid leukaemia (CML). In most cases, the drug is well tolerated: however, side effects can be seen. Hair loss and paronychia inflammation were often reported with Imatinib, but total alopecia was rarely mentioned. We report a CML patient who was presented with alopecia and paronychia inflammation probably induced by imatinib therapy. We have successfully treated our patient by cessation and then re-applying therapy with lower doses after improvement of lesions and have not found a similar report in literature. © 2013 Elsevier Ltd.
dc.identifier.DOI-ID10.1016/j.transci.2013.01.002
dc.identifier.issn18781683
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/17279
dc.language.isoEnglish
dc.subjectAlopecia
dc.subjectBenzamides
dc.subjectHumans
dc.subjectLeukemia, Myelogenous, Chronic, BCR-ABL Positive
dc.subjectMale
dc.subjectMiddle Aged
dc.subjectNecrosis
dc.subjectParonychia
dc.subjectPiperazines
dc.subjectPyrimidines
dc.subjectimatinib
dc.subjectmometasone furoate
dc.subjectsteroid
dc.subjectadult
dc.subjectalopecia
dc.subjectarticle
dc.subjectcancer chemotherapy
dc.subjectcase report
dc.subjectchronic myeloid leukemia
dc.subjectcorticosteroid therapy
dc.subjectdiarrhea
dc.subjectdrug eruption
dc.subjectdrug withdrawal
dc.subjecteosinophilia
dc.subjecthuman
dc.subjecthuman tissue
dc.subjectmale
dc.subjectnail disease
dc.subjectnail necrosis
dc.subjectnephrectomy
dc.subjectorbit edema
dc.subjectpoliomyelitis
dc.subjectskin biopsy
dc.subjectskin necrosis
dc.subjectsteroid therapy
dc.titleSuccessful management of imatinib despite alopecia and nail necrosis
dc.typeArticle

Files

Collections

Scopus Koleksiyonu