Evaluation of retinochoroidal tissues in third trimester pregnants: An optical coherence tomography angiography study

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dc.contributor.authorYildirim A.
dc.contributor.authorKurt E.
dc.contributor.authorAltinisik M.
dc.contributor.authorUyar Y.
dc.date.accessioned2024-07-22T08:05:24Z
dc.date.available2024-07-22T08:05:24Z
dc.date.issued2022
dc.description.abstractIntroduction: The structural and vascular changes in the retina and choroid in women in the third trimester of pregnancy were analyzed using optical coherence tomography angiography (OCTA). Methods: Forty women in the third trimester of uncomplicated pregnancy and 40 age-matched healthy women were included. Vascular density (VD) in the superficial and deep capillary plexuses (SCP/DCP), foveal density (FD), and foveal avascular zone (FAZ) area and perimetry measured with OCTA, as well as OCT measurements of central macular thickness (CMT) and choroidal thickness (CT) were compared between the groups. Correlations between structural OCT parameters and vascular OCTA metrics were analyzed. Results: The mean gestational age was 34 (28–41) weeks. Mean age was comparable in the groups (p = 0.732). The pregnant women had significantly higher parafoveal DCP-VD (p = 0.015), FAZ area (p = 0.044), and FD (p = 0.002). Mean subfoveal CT was 21 µm higher in pregnant women but was not significant (p = 0.472). There was no difference in CMT (p = 0.448). FAZ metrics were positively correlated with CT in pregnants and with CMT in the control group (p < 0.05). Parafoveal VD was negatively correlated with CT in the control group (p < 0.05). After adjusting for CT and CMT, the significant difference in VD and FD persisted (p < 0.05), while the difference in FAZ area lost significance (p > 0.05). Conclusions: Considering the effects of the probable covariant factors CMT and CT, systemic changes in pregnant women in their third trimester may cause an increase in VD in the macula and parafoveal DCP. © The Author(s) 2020.
dc.identifier.DOI-ID10.1177/1120672120966566
dc.identifier.issn11206721
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/13129
dc.language.isoEnglish
dc.publisherSAGE Publications Ltd
dc.subjectFemale
dc.subjectFluorescein Angiography
dc.subjectHumans
dc.subjectInfant
dc.subjectMacula Lutea
dc.subjectPregnancy
dc.subjectPregnancy Trimester, Third
dc.subjectRetinal Vessels
dc.subjectTomography, Optical Coherence
dc.subjectadult
dc.subjectArticle
dc.subjectbest corrected visual acuity
dc.subjectblood vessel density
dc.subjectcentral macular thickness
dc.subjectchoroid plexus
dc.subjectchoroidal thickness
dc.subjectclinical article
dc.subjectcomparative effectiveness
dc.subjectcontrolled study
dc.subjectcorrelation analysis
dc.subjectcytology
dc.subjectdeep capillary plexus
dc.subjectdeep capillary plexus
dc.subjectfemale
dc.subjectfoveal avascular zone
dc.subjectfoveal density
dc.subjectfoveal thickness
dc.subjectgestational age
dc.subjecthuman
dc.subjectimage quality
dc.subjectmacular thickness
dc.subjectmiddle aged
dc.subjectoptical coherence tomography
dc.subjectoptical coherence tomography angiography
dc.subjectparafoveal deep retinal capillary plexus
dc.subjectperimetry
dc.subjectpregnancy
dc.subjectpregnant woman
dc.subjectretina blood flow
dc.subjectretina blood vessel
dc.subjectretina cell
dc.subjectretina fovea
dc.subjectretina macula lutea
dc.subjectretinal nerve fiber layer thickness
dc.subjectretinochoroidal tissue
dc.subjectsubfoveal choroidal thickness
dc.subjectsuperficial capillary plexus
dc.subjectthird trimester pregnancy
dc.subjectdiagnostic imaging
dc.subjectfluorescence angiography
dc.subjectinfant
dc.subjectoptical coherence tomography
dc.subjectretina macula lutea
dc.subjectthird trimester pregnancy
dc.titleEvaluation of retinochoroidal tissues in third trimester pregnants: An optical coherence tomography angiography study
dc.typeArticle

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