Surgical Antimicrobial Prophylaxis Compliance in Turkey: Data from the Prospective, Observational, Multicenter Survey Including 7,978 Surgical Patients

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dc.contributor.authorÇelik Ekinci S.
dc.contributor.authorYenilmez E.
dc.contributor.authorAkengin Öcal G.
dc.contributor.authorSönmezer M.I.
dc.contributor.authorTarakçı A.
dc.contributor.authorAygün C.
dc.contributor.authorAkdağ D.
dc.contributor.authorSeyman D.
dc.contributor.authorAşık C.
dc.contributor.authorZerdali E.
dc.contributor.authorYılmaz Karadağ F.
dc.contributor.authorKaya Ş.
dc.contributor.authorÇelik M.
dc.contributor.authorÇifci Ş.
dc.contributor.authorYıldız İ.E.
dc.contributor.authorÇölkesen F.
dc.contributor.authorAkgül F.
dc.contributor.authorAldemir I.
dc.contributor.authorBozdağ M.
dc.contributor.authorÖzer D.
dc.contributor.authorHızmalı L.
dc.contributor.authorCanbolat Ünlü E.
dc.contributor.authorGür Altunay D.
dc.contributor.authorŞahin A.
dc.contributor.authorÜnlü G.
dc.contributor.authorGençalioğlu A.E.
dc.contributor.authorTekin Şahin S.
dc.contributor.authorÖzdemir Y.
dc.contributor.authorÜnlü S.
dc.contributor.authorSingil S.
dc.contributor.authorAltıntaş J.
dc.contributor.authorAkkaya Işık S.
dc.contributor.authorGül I.
dc.contributor.authorTuna N.
dc.contributor.authorŞimşek S.
dc.contributor.authorÖzgüler M.
dc.contributor.authorElbir Kılıç P.
dc.contributor.authorIşık M.E.
dc.contributor.authorKarakuş A.
dc.contributor.authorKıratlı K.
dc.contributor.authorYardımcı A.C.
dc.contributor.authorVolkan S.
dc.contributor.authorOlçar Y.
dc.contributor.authorÇakır Y.
dc.contributor.authorÖzer Yılmaz N.
dc.contributor.authorKaraayvaz S.
dc.contributor.authorBatırel A.
dc.contributor.authorDuran Z.C.
dc.contributor.authorRaşa H.K.
dc.contributor.authorKöse Ş.
dc.date.accessioned2024-07-22T08:01:26Z
dc.date.available2024-07-22T08:01:26Z
dc.date.issued2024
dc.description.abstractBackground: Surgical antimicrobial prophylaxis (SAP) is the peri-operative administration of antimicrobial agents. Compliance rates vary worldwide from 15% to 84.3%, with studies in Turkey not exceeding 35%. The aim of this multicenter study was to determine the rate of appropriate antibiotic class, timing, and duration as well as discharge prescriptions in Turkey. Thus, we aimed to determine the rate of full compliance with SAP procedures in our country Patients and Methods: This multicenter, prospective, observational, descriptive study was conducted in 47 hospitals from 28 provinces in seven different regions of Turkey. Patients over 18 years of age in all surgical units between June 6, 2022, and June 10, 2022, were included in the study. Results: Of the 7,978 patients included in the study, 332 were excluded from further analyses because of pre-existing infection, and SAP compliance analyses were performed on the remaining 7,646 cases. The antibiotic most commonly used for SAP was cefazolin (n = 4,701; 61.5%), followed by third-generation cephalosporins (n = 596; 7.8%). The most common time to start SAP was within 30 minutes before surgery (n = 2,252; 32.5%), followed by 30 to 60 minutes before surgery (n = 1,638; 23.6%). Surgical antimicrobial prophylaxis duration was <24 hours in 3,516 (50.7%) patients and prolonged until discharge in 1,505 (21.7%) patients. Finally, the actual proportion of patients compliant with SAP was 19% (n = 1,452) after omitting 4,458 (58.3%) patients who were prescribed oral antibiotic agents at discharge as part of a prolonged SAP. Conclusions: Surgical antimicrobial prophylaxis compliance rates are still very low in Turkey. Prolonged duration of SAP and especially high rate of antibiotic prescription at discharge are the main reasons for non-compliance with SAP. Copyright 2024, Mary Ann Liebert, Inc., publishers.
dc.identifier.DOI-ID10.1089/sur.2023.243
dc.identifier.issn10962964
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/11457
dc.language.isoEnglish
dc.publisherMary Ann Liebert Inc.
dc.subjectampicillin
dc.subjectcefazolin
dc.subjectcephalosporin derivative
dc.subjectpiperacillin plus tazobactam
dc.subjectsultamicillin
dc.subjectadult
dc.subjectaged
dc.subjectantibiotic prophylaxis
dc.subjectArticle
dc.subjectelective surgery
dc.subjectemergency surgery
dc.subjectfemale
dc.subjecthealth survey
dc.subjecthospital discharge
dc.subjecthuman
dc.subjectlaparoscopic surgery
dc.subjectmajor clinical study
dc.subjectmale
dc.subjectmulticenter study
dc.subjectobservational study
dc.subjectopen surgery
dc.subjectpatient compliance
dc.subjectperioperative care
dc.subjectpreoperative period
dc.subjectprospective study
dc.subjectsurgical antimicrobial prophylaxis
dc.subjectsurgical infection
dc.subjectsurgical patient
dc.subjecttreatment duration
dc.subjectTurkey (republic)
dc.subjectvery elderly
dc.titleSurgical Antimicrobial Prophylaxis Compliance in Turkey: Data from the Prospective, Observational, Multicenter Survey Including 7,978 Surgical Patients
dc.typeArticle

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