Enhanced biocompatibility of GPC by silver ion implantation

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Date

2005

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Abstract

Biocompatible Glassy Polymeric Carbon (GPC) is used for artificial heart valves and in other biomedical applications. Although it is ideally suited for implants in the blood stream, tissue that normally forms around the moving parts of a GPC heart valve sometimes loses adhesion and creates embolisms downstream. Here we compare silver ion implantation and silver deposition, each of which strongly inhibits cell attachment on GPC. Inhibition of cell adhesion is a desirable improvement to current GPC cardiac implants. In vitro biocompatibility tests have been carried out with model cell lines to demonstrate that traces of silver can favorably influence the surface of GPC for biomedical applications. © 2006 Materials Research Society.

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Keywords

Biocompatibility , Biomedical engineering , Blood , Cell adhesion , Glass , Heart valve prostheses , Ion implantation , Silver , Biomedical applications. , Glassy Polymeric Carbon (GPC) , Heart valves , Implants (surgical)

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http://akademikarsiv.cbu.edu.tr:4000/handle/123456789/19577

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