Metabolic predictors for early identification of fatty liver using doppler and B-mode ultrasonography in overweight and obese adolescents

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dc.contributor.authorOzkol M.
dc.contributor.authorErsoy B.
dc.contributor.authorKasirga E.
dc.contributor.authorTaneli F.
dc.contributor.authorBostanci I.E.
dc.contributor.authorOzhan B.
dc.date.accessioned2024-07-22T08:20:48Z
dc.date.available2024-07-22T08:20:48Z
dc.date.issued2010
dc.description.abstractThe aims of our study were: (1) to evaluate the frequency of asymptomatic fatty liver disease (FLD) using both Doppler and B-mode ultrasound (US) in overweight and obese adolescents; (2) to compare metabolic findings of fatty liver (FL) assessed by two methods; and (3) to evaluate metabolic predictors of FL shown by these methods. Fifty-nine overweight and obese adolescents aged between 9.0 and 17.0 years and 41 non-obese healthy adolescents were included in this study. B-mode and right hepatic vein Doppler ultrasonography (US) were performed and anthropometric indices, lipid profiles, and adiponectin levels were evaluated in all adolescents. HDL-C levels were significantly lower in patients with FL detected by Doppler US compared to patients without FL (p∈<∈0.05). HDL-C levels were inversely correlated with presence of FL assessed by two methods (r∈=∈-0.285, p∈=∈0.004; r∈=∈-0.328, p∈=∈0.001, respectively) and adiponectin levels were correlated with presence of FL only detected by B-mode US (r∈=∈-0.263, p∈=∈0.008). Adiponectin levels were significantly lower in patients with FL than those without FL assessed by B-Mode US (p∈=∈0.049). Multiple regression analysis revealed that HDL-C levels was the most important predictor of FL assessed by Doppler US (p∈=∈0.027), while body mass index was the determinant of FL assessed by two methods (p∈<∈0.001) in asymptomatic overweight and obese adolescents. It was found that FLD, identified by both B-mode and Doppler US, is seen frequently in asymptomatic overweight and obese adolescents. Elevated BMI is associated with increased risk of FL assessed by two ultrasonographic methods. When using Doppler US, low HDL-C levels can be used as a good predictor for presence of FLD in overweight and obese adolescents. © 2010 Springer-Verlag.
dc.identifier.DOI-ID10.1007/s00431-010-1227-2
dc.identifier.issn03406199
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/18331
dc.language.isoEnglish
dc.subjectAdolescent
dc.subjectChild
dc.subjectCholesterol, HDL
dc.subjectDisease Progression
dc.subjectEarly Diagnosis
dc.subjectFatty Liver
dc.subjectFemale
dc.subjectFollow-Up Studies
dc.subjectHumans
dc.subjectMale
dc.subjectObesity
dc.subjectOverweight
dc.subjectPrognosis
dc.subjectRisk Factors
dc.subjectUltrasonography, Doppler
dc.subjectadiponectin
dc.subjecthigh density lipoprotein cholesterol
dc.subjectlipid
dc.subjectadolescent
dc.subjectadult
dc.subjectanthropometry
dc.subjectarticle
dc.subjectbody mass
dc.subjectchild
dc.subjectDoppler echocardiography
dc.subjectfatty liver
dc.subjectfemale
dc.subjectgroups by age
dc.subjecthuman
dc.subjectmajor clinical study
dc.subjectmale
dc.subjectmetabolic disorder
dc.subjectobesity
dc.subjectpreschool child
dc.subjectpriority journal
dc.subjectschool child
dc.titleMetabolic predictors for early identification of fatty liver using doppler and B-mode ultrasonography in overweight and obese adolescents
dc.typeArticle

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