Efficacy of ropivacaine and ropivacaine+neostigmine combination for elective cesarean section; [Sezaryen operasyonlarinda i̇ntratekal ropivakain ve ropivakain + neostigminin anestezik etkilerinin karşilaştirilmasi]
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2007
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Abstract
The objective of this study is to compare the efficacy of intrathecal ropivacaine and the combination of ropivacaine with neostigmine for elective cesarean sectio. Forty ASA grade I-II parturients were scheduled for elective cesarean delivery under spinal anesthesia. The patients were randomly assigned into two groups. Grup 1 received 15 mg of 0.75 % hyperbaric ropivacaine. Group 2 received 15 mg of % 0.75 hyperbaric ropivacaine combined with 25 μgr neostigmine. Hyperbaric solutions were made with 2 ml of 0.75 % ropivacaine and 0.5 ml of 20 % dextrose. After injection of the spinal medication patients were turned head up 20-30° supine. Baseline mean arterial blood pressure, heart rate, pulse oximetry were recorded and every 5 min during the surgery the same parameters also sensory block level, motor block degree were recorded. Sensory block, motor block and VAS scores were recorded postoperatively at first, second and forth hour. Time until first analgesic requirement and total analgesic consumption in the first 24 hours were recorded. Homodynamic changes, sensory block level, motor block degree, VAS scores, time until first analgesic requirement, postoperative total analgesic consumption were similar among two groups. No statistically noteworthy difference was determined. In conclusion, the time until first analgesic requirement is increased by 25 μgr neostigmine without any adverse effect although there wasn't any significant difference.