Serum brain-derived neurotrophic factor (BDNF) levels in schizophrenic patients with depressive sypmptoms: A preliminary study

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dc.contributor.authorEsen-Danaci A.
dc.contributor.authorAydemir Ö.
dc.contributor.authorDeveci A.
dc.contributor.authorTaneli F.
dc.contributor.authorTaşkin O.
dc.date.accessioned2024-07-22T08:21:24Z
dc.date.available2024-07-22T08:21:24Z
dc.date.issued2009
dc.description.abstractObjectives: Evidence from clinical, pharmacological and animal studies, have led to neurodevelopment, neurodegeneration, and dopamine hypotheses, and to the investigation of BDNF as a potential candidate molecule in the pathophysiology of schizophrenia. The aim of this study is to investigate the BNDF levels of schizophrenic patients with depression and compare them with major depression patients and controls in order to understand the nature of depressive symptoms seen in schizophrenia. Methods: The BDNF levels of eight schizophrenic patients with depressive symptomatology (SD) were compared with two control groups. The first group consisted of major depressed patients (MDD) (n=24) and the second was the healthy control group (n=26). Results: SD group had BDNF levels similar to control group and MDD group had significantly lower levels than the other two groups. Conclusion: This difference of BDNF levels between schizophrenia with depression group and major depression group supports the hypothesis of distinct etiologies.
dc.identifier.issn13029657
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/18580
dc.language.isoEnglish
dc.subjectatypical antipsychotic agent
dc.subjectbrain derived neurotrophic factor
dc.subjectimmunoglobulin antibody
dc.subjectimmunoglobulin Y
dc.subjectadult
dc.subjectaged
dc.subjectarticle
dc.subjectblood level
dc.subjectblood sampling
dc.subjectclinical article
dc.subjectclinical assessment
dc.subjectcomparative study
dc.subjectcontrolled study
dc.subjectdepression
dc.subjectenzyme linked immunosorbent assay
dc.subjectfemale
dc.subjecthuman
dc.subjectmajor depression
dc.subjectmale
dc.subjectpathophysiology
dc.subjectschizophrenia
dc.subjectstatistical significance
dc.titleSerum brain-derived neurotrophic factor (BDNF) levels in schizophrenic patients with depressive sypmptoms: A preliminary study
dc.typeArticle

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