Targeted singlet oxygen generation using different DNA-interacting perylene diimide type photosensitizers

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dc.contributor.authorDinçalp H.
dc.contributor.authorKIzIlok Ş.
dc.contributor.authorIçli S.
dc.date.accessioned2024-07-22T08:16:49Z
dc.date.available2024-07-22T08:16:49Z
dc.date.issued2014
dc.description.abstractSinglet oxygen quantum yields (ΦΔ) of different perylene diimides (PDIs) containing phenyl (PDI-Ph), pyrene (PDI-Pyr), and indole (PDI-In) units in bay positions of the ring were determined using 1,3-diphenylisobenzofuran (DPBF) method in toluene/methanol (99:1) system. Pyrene-substituted PDI were the most efficient singlet oxygen generator among the investigated photosensitizers with a quantum yield of Φ Δ=0.93 in toluene/methanol. Additionally, their binding affinities to G-quadruplex DNA structure were investigated by steady-state measurements. There were marked red shifts of absorbance bands for PDI-Pyr/DNA strand complexes with respect to the absorption maxima of DNA-free solution of PDI-Pyr in phosphate buffer at pH 6. © 2014 Springer Science+Business Media New York.
dc.identifier.DOI-ID10.1007/s10895-014-1372-5
dc.identifier.issn10530509
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/16887
dc.language.isoEnglish
dc.publisherSpringer New York LLC
dc.subjectDNA
dc.subjectG-Quadruplexes
dc.subjectImides
dc.subjectMolecular Structure
dc.subjectPerylene
dc.subjectPhotosensitizing Agents
dc.subjectQuantum Theory
dc.subjectSinglet Oxygen
dc.subjectBinding energy
dc.subjectCharge transfer
dc.subjectGas generators
dc.subjectLiquid crystal polymers
dc.subjectOxygen
dc.subjectPhotosensitizers
dc.subjectPyrene
dc.subjectQuantum yield
dc.subjectDNA
dc.subjectguanine quadruplex
dc.subjectimide
dc.subjectperylene
dc.subjectperylenediimide
dc.subjectphotosensitizing agent
dc.subjectsinglet oxygen
dc.subjectBinding affinities
dc.subjectDPBF method
dc.subjectG-quadruplexes
dc.subjectPerylenediimides
dc.subjectSinglet oxygen
dc.subjectSinglet oxygen generation
dc.subjectSinglet oxygen generators
dc.subjectSteady-state measurements
dc.subjectanalogs and derivatives
dc.subjectchemical structure
dc.subjectchemistry
dc.subjectmetabolism
dc.subjectquantum theory
dc.subjectDNA
dc.titleTargeted singlet oxygen generation using different DNA-interacting perylene diimide type photosensitizers
dc.typeArticle

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