Differences in the cellular and humoral immune system between middle-aged men with different intensity and duration of physically training

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dc.contributor.authorBuyukyazi G.
dc.contributor.authorKutukculer N.
dc.contributor.authorKutlu N.
dc.contributor.authorGenel F.
dc.contributor.authorKaradeniz G.
dc.contributor.authorOzkutuk N.
dc.date.accessioned2024-07-22T08:24:16Z
dc.date.available2024-07-22T08:24:16Z
dc.date.issued2004
dc.description.abstractAim. The effects of acute exercise on immune system and serum magnesium and iron have been investigated in recent years. However, data related to the comparisons of long-term physical training with different intensity and duration are limited. Methods. The association between long-term physical training and cellular (lymphocyte phenotyping) and humoral immune parameters (serum immunoglobulins) and serum magnesium and iron values in the middle-aged men was investigated. Eleven male master athletes (MA) performing high intensity and long duration training, 11 male recreational athletes (RA) performing moderate intensity and duration training (>10 years) participated. Eleven male sedentary individuals were enrolled as control group (CG). Results. The percentages of total CD3+ T cells, CD4+ T helper, CD8+ T suppressor/cytotoxic, CD19+ B cells, natural killer cells, HLA-DR+ active T cells and CD4/CD8 ratios did not show any significant difference among 3 groups. In MA, VO2max values showed a significant negative correlation with CD4+ T helper cells. There were no significant differences among MA, RA and CG in terms of IgG, IgA, and IgM concentrations. There was a significant correlation between VO 2max and IgG in RA. Iron, iron binding capacity and ferritin were found similar in all groups, but serum magnesium level in MA was significantly lower than RA and CG. Conclusion. No exact data to support immunosuppression or immunostimulation could be obtained except a significant negative correlation between CD4+ T helper cells and VO2max values in MA and a positive correlation between serum IgG and VO2max ivalues in RA. These findings may be the indirect markers of cellular immune system suppression by intensive exercises and stimulation of IgG production by moderate exercises.
dc.identifier.issn00224707
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/19889
dc.language.isoEnglish
dc.subjectCase-Control Studies
dc.subjectExercise
dc.subjectFerritins
dc.subjectHumans
dc.subjectImmune System
dc.subjectImmunity
dc.subjectImmunity, Cellular
dc.subjectImmunoglobulins
dc.subjectKiller Cells, Natural
dc.subjectLeukocytes
dc.subjectMagnesium
dc.subjectMale
dc.subjectMiddle Aged
dc.subjectPhysical Education and Training
dc.subjectSports
dc.subjectT-Lymphocytes
dc.subjectTime Factors
dc.subjectferritin
dc.subjectHLA DR antigen
dc.subjectimmunoglobulin
dc.subjectimmunoglobulin A
dc.subjectimmunoglobulin G
dc.subjectimmunoglobulin M
dc.subjectmagnesium
dc.subjectadult
dc.subjectarticle
dc.subjectathlete
dc.subjectB lymphocyte
dc.subjectcellular immunity
dc.subjectcontrolled study
dc.subjectcorrelation analysis
dc.subjectendurance
dc.subjectexercise
dc.subjectferritin blood level
dc.subjecthelper cell
dc.subjecthuman
dc.subjecthuman experiment
dc.subjecthumoral immunity
dc.subjectimmunoglobulin blood level
dc.subjectimmunoglobulin production
dc.subjectimmunostimulation
dc.subjectiron binding capacity
dc.subjectiron blood level
dc.subjectlymphocyte count
dc.subjectmagnesium blood level
dc.subjectmale
dc.subjectnatural killer cell
dc.subjectnormal human
dc.subjectphenotype
dc.subjectsitting
dc.subjectT lymphocyte
dc.subjecttraining
dc.titleDifferences in the cellular and humoral immune system between middle-aged men with different intensity and duration of physically training
dc.typeArticle

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