Autopsy findings of a case with oxalosis
No Thumbnail Available
Date
2009
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
Oxalosis, deposition of calcium oxalate in tissues, is the final stage of hyperoxaluric syndromes. Being a rare entity, it is often missed, or the diagnosis is delayed, since the definitive diagnosis requires special laboratory tests. Kidneys, the walls of blood vessels, and bones are the major sites for crystal deposition. We report the autopsy findings of a 4-year-old girl who presented with end-stage renal disease in which the clinical presentation was consistent with primary hyperoxaluria Type I. The case is unusual, as there was extensive crystal deposition throughout the body, including in tissues that are rarely involved, such as ovaries, fallopian tubes, uterus, thymus, salivary glands, pancreas, and bladder. © 2009 Society for Pediatric Pathology.
Description
Keywords
Calcium Oxalate , Child, Preschool , Fatal Outcome , Female , Humans , Hyperoxaluria, Primary , Kidney , Kidney Failure, Chronic , Microscopy, Polarization , calcium , creatinine , abdominal pain , anamnesis , article , autopsy , bladder , calcium blood level , case report , child , creatinine blood level , echocardiography , female , heart auscultation , heart left ventricle hypertrophy , hospital admission , human , human tissue , kidney calcification , kidney failure , liver biopsy , liver function test , lung artery pressure , lung edema , ovary , oxalosis 1 , pancreas , pericardial effusion , peritoneal dialysis , peritonitis , physical examination , preschool child , priority journal , pulmonary hypertension , salivary gland , systolic heart murmur , thymus , ultrasound , uterine tube , uterus , X ray analysis