Venous thromboembolism prophylaxis in major orthopaedic surgery: A multicenter, prospective, observational study; [Majör ortopedik cerrahilerde venöz tromboemboli profilaksisi: Çokmerkezli, prospektif, gözlem çalışması]

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dc.contributor.authorAltintas F.
dc.contributor.authorGurbuz H.
dc.contributor.authorErdemli B.
dc.contributor.authorAtilla B.
dc.contributor.authorUstaoglu R.G.
dc.contributor.authorOzic U.
dc.contributor.authorSavk O.
dc.contributor.authorBayram H.
dc.contributor.authorMemik R.
dc.contributor.authorAkgun I.
dc.contributor.authorGogus A.
dc.contributor.authorPestilci F.
dc.contributor.authorKonal A.
dc.contributor.authorArgun M.
dc.contributor.authorOzturk I.
dc.contributor.authorDabak N.
dc.contributor.authorBilgen O.F.
dc.contributor.authorSerin E.
dc.contributor.authorOnder C.
dc.contributor.authorSimsek A.
dc.contributor.authorTozun R.
dc.contributor.authorKinik H.
dc.date.accessioned2024-07-22T08:22:34Z
dc.date.available2024-07-22T08:22:34Z
dc.date.issued2008
dc.description.abstractObjectives: We investigated risk factors for venous thromboembolism (VTE), prophylaxis measures employed, and incidence of symptomatic deep venous thrombosis (DVT) and pulmonary embolism (PE) in patients undergoing major orthopaedic surgery (MOS). Methods: An open, multicenter, prospective, observational study was conducted in 21 medical centers, comprising 899 patients. Of these, 316 patients (35.2%) underwent total hip arthroplasty (THA), 328 patients (36.5%) underwent total knee arthroplasty (TKA), and 255 patients (28.4%) underwent surgery for hip fractures (HF). Pharmacologic prophylaxis was employed in all the patients. Results: Risk factors for VTE were seen in 73.2% of the patents, the most common being obesity (72%) and prolonged immobilization (36.3%). Low-molecular-weight heparin (91.1%) and fondaparinux (8.9%) were used for prophylaxis, which was short-term in 273 patients (30.4%) and long-term in 626 patients (69.6%). Mechanical prophylaxis was performed with compression stockings in 610 patients (67.9%) and by intermittent pneumatic compression in 67 patients (7.5%). During three-months of follow-up, symptomatic DVT and PE were seen in eight (0.9%) and four patients (0.4%), respectively. Mortality occurred in 10 patients (1.1%). Complications of major and minor bleeding were seen in eight (0.9%) and 40 (4.5%) patients, respectively. Conclusion: Effective VTE prophylaxis is associated with low risk of clinically apparent DVT and PE in MOS. © 2008 Turkish Association of Orthopaedics and Traumatology.
dc.identifier.DOI-ID10.3944/AOTT.2008.322
dc.identifier.issn1017995X
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/19147
dc.language.isoTurkish
dc.publisherTurkish Association of Orthopaedics and Traumatology
dc.rightsAll Open Access; Gold Open Access; Green Open Access
dc.titleVenous thromboembolism prophylaxis in major orthopaedic surgery: A multicenter, prospective, observational study; [Majör ortopedik cerrahilerde venöz tromboemboli profilaksisi: Çokmerkezli, prospektif, gözlem çalışması]
dc.typeArticle

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