Opening the cardiac chambers does not make any difference in P300 measurement

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dc.contributor.authorIskesen I.
dc.contributor.authorYilmaz H.
dc.contributor.authorYildirim F.
dc.contributor.authorSelcuki D.
dc.date.accessioned2024-07-22T08:23:17Z
dc.date.available2024-07-22T08:23:17Z
dc.date.issued2006
dc.description.abstractObjective. Cognitive brain dysfunction after open heart surgery is a serious complication caused by cardiopulmonary bypass (CPB). The presence of gaseous and/or particulate emboli in the CPB circuit and cerebral hypoperfusion may be the causes of neurologic problems after cardiac operations. Methods. In this prospective study we examined 42 consecutive cardiac surgery patients (24 mitral valve replacement [MVR] and 18 coronary artery bypass grafting [CABG] patients). In addition to determination of clinical measurements, cognitive brain function was measured objectively by P300 auditory-evoked potentials before operation, at day 7, and at 4-month follow-up. Electroencephalographic evaluations were also performed. Results. In preoperative measures there was no difference between the groups (peak latencies in the MVR group were 324 ± 8 milliseconds; CABG group, 318 ± 6 milliseconds; P > .05). At day 7, cognitive P300 auditory-evoked potentials were significantly impaired (prolonged) in both groups compared to preoperative values (MVR group, 347 ± 7 milliseconds; CABG group, 342 ± 7 milliseconds; P < .05). P300 measurements almost returned to normal at 4-month follow-up (MVR group, 331 ± 6 milliseconds; CABG group, 319 ± 8 milliseconds; P > .05 compared to preoperative values). One week and 4 months after surgery no difference between the 2 groups could be found (P > .05). Conclusion. Postoperative patients had prolonged P300 values according to the preoperative measurements and we have not found any difference between the groups whether cardiac chambers were opened or not. © 2006 Forum Multimedia Publishing, LLC.
dc.identifier.DOI-ID10.1532/HSF98.20061056
dc.identifier.issn10983511
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/19467
dc.language.isoEnglish
dc.subjectAdult
dc.subjectCognition Disorders
dc.subjectCoronary Artery Bypass
dc.subjectEvent-Related Potentials, P300
dc.subjectFemale
dc.subjectHeart Valve Prosthesis Implantation
dc.subjectHumans
dc.subjectMale
dc.subjectMiddle Aged
dc.subjectMitral Valve
dc.subjectProspective Studies
dc.subjectadult
dc.subjectarticle
dc.subjectcardiopulmonary bypass
dc.subjectclinical article
dc.subjectclinical trial
dc.subjectcognitive defect
dc.subjectcontrolled clinical trial
dc.subjectcontrolled study
dc.subjectcoronary artery bypass graft
dc.subjectdiagnostic value
dc.subjectelectroencephalography
dc.subjectevoked auditory response
dc.subjectfemale
dc.subjectfollow up
dc.subjecthuman
dc.subjectlatent period
dc.subjectmale
dc.subjectmitral valve replacement
dc.subjectopen heart surgery
dc.subjectpostoperative period
dc.subjectpreoperative evaluation
dc.subjectpriority journal
dc.subjectprospective study
dc.subjectstatistical significance
dc.subjectcognitive defect
dc.subjectcomparative study
dc.subjectcoronary artery bypass graft
dc.subjectevent related potential
dc.subjectheart valve replacement
dc.subjectmiddle aged
dc.subjectmitral valve
dc.subjectpathophysiology
dc.titleOpening the cardiac chambers does not make any difference in P300 measurement
dc.typeArticle

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