A comparative study of type 1 neovascularization: Neovascular age-related macular degeneration versus pachychoroid neovasculopathy

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dc.contributor.authorAltinisik M.
dc.contributor.authorKurt E.
dc.contributor.authorSonmezer P.
dc.contributor.authorKayikcioglu O.
dc.contributor.authorIlker S.S.
dc.date.accessioned2024-07-22T08:04:13Z
dc.date.available2024-07-22T08:04:13Z
dc.date.issued2022
dc.description.abstractPurpose: This study aimed to compare type 1 choroidal neovascularization (CNV) characteristics in eyes with pachychoroid neovasculopathy (PNV) and neovascular age-related macular degeneration (nAMD) using optical coherence tomography angiography (OCTA). Methods: Treatment naive 23 eyes of 23 patients with PNV and 24 eyes of 24 patients with nAMD were evaluated. The height of pigment epithelial detachment (PED) and the central macular thickness were determined. OCTA sensitivity, CNV area, morphological patterns, and retinal superficial capillary plexus vessel density (SCP-VD) values were compared. The frequency of quiescent CNV, subretinal hyperreflective exudation (SHE), subretinal/intraretinal fluid, serous PED, double-layer sign (DLS), and pachyvessels were noted. Results: CNV was detected on OCTA in 83.3% of nAMD eyes and 91.3% of PNV eyes (p = 0.66). Indistinct pattern was more common (74% vs 50%) and the CNV area (mm2) was smaller in PNV (0.77 ± 0.54 vs 1.57 ± 1.43) but did not reach significant levels (p = 0.27 and 0.33 respectively). SCP-VD was similar between the groups (p = 0.38). Statistically significant differences were found between groups in age and subfoveal choroidal thickness (p < 0.05). DLS and pachyvessels were found to be more frequently in PNV (p < 0.05). However, both groups had similar rates of quiescent CNV, SHE, subretinal/intraretinal fluid, and serous PED (p > 0.05). Conclusion: Morphological features, area, and activation findings of type 1 CNV may play a limited role in differentiating nAMD and PNV cases. © The Author(s) 2021.
dc.identifier.DOI-ID10.1177/11206721211037828
dc.identifier.issn11206721
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/12596
dc.language.isoEnglish
dc.publisherSAGE Publications Ltd
dc.subjectChoroid
dc.subjectChoroidal Neovascularization
dc.subjectFluorescein Angiography
dc.subjectHumans
dc.subjectMacular Degeneration
dc.subjectRetinal Detachment
dc.subjectRetrospective Studies
dc.subjectTomography, Optical Coherence
dc.subjectadult
dc.subjectage related macular degeneration
dc.subjectaged
dc.subjectArticle
dc.subjectbest corrected visual acuity
dc.subjectblood vessel density
dc.subjectcataract extraction
dc.subjectcentral macular thickness
dc.subjectchoroid capillary layer
dc.subjectclinical article
dc.subjectcomparative study
dc.subjectcomputer assisted tomography
dc.subjectdouble-layer sign
dc.subjectfemale
dc.subjectfluorescence angiography
dc.subjecthuman
dc.subjectintraocular pressure
dc.subjectmale
dc.subjectmiddle aged
dc.subjectmultimodal imaging
dc.subjectneovascularization (pathology)
dc.subjectophthalmoscopy
dc.subjectoptical coherence tomography
dc.subjectoptical coherence tomography angiography
dc.subjectpachychoroid neovasculopathy
dc.subjectpachyvessel
dc.subjectphotography
dc.subjectpolypoidal choroidal vasculopathy
dc.subjectradial peripapillary capillary
dc.subjectretina blood vessel
dc.subjectretina detachment
dc.subjectretinal nerve fiber layer thickness
dc.subjectretinal superficial capillary plexus vessel density
dc.subjectretinal thickness
dc.subjectretrospective study
dc.subjectspectral domain optical coherence tomography
dc.subjectspectral sensitivity
dc.subjectsubfoveal choroidal thickness
dc.subjectsubretinal fluid
dc.subjectsubretinal hyperreflective exudation
dc.subjectsubretinal neovascularization
dc.subjectvisual acuity
dc.subjectwet macular degeneration
dc.subjectchoroid
dc.subjectmacular degeneration
dc.subjectprocedures
dc.subjectretina detachment
dc.subjectsubretinal neovascularization
dc.subjectvascularization
dc.titleA comparative study of type 1 neovascularization: Neovascular age-related macular degeneration versus pachychoroid neovasculopathy
dc.typeArticle

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