Differential pulse polarographic determination of Enalapril maleate

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Date

2003

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Abstract

A differential pulse polarographic (DPP) method has been developed for the quantitative analysis of enalapril maleate. Enalapril maleate gives a peak at -1.4 V in methanol. A calibration curve was constructed for the 20 -100 μg ml-1 concentration range. As a reference method, a reversed phase high performance liquid chromatographic procedure has been developed. Commercially available tablets were analysed by the two methods. Statistical evaluations indicated that there was no significant difference between the mean values and precisions of the two methods at a 95% confidence level.

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Keywords

enalapril maleate , methanol , article , calibration , commercial phenomena , concentration (parameters) , differential pulse polarography , drug determination , high performance liquid chromatography , quantitative analysis , statistical analysis , tablet

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http://akademikarsiv.cbu.edu.tr:4000/handle/123456789/20189

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