Generalized mean-field theory relating helix tilt in a bilayer to lipid disorder
Abstract
We present a generalized theory relating the helix tilt angle in a bilayer to lipid disorder. In doing so, we consider a theory performed earlier [Biophys. Chem., 86 (2000) 79] and generalize it within a nonextensive formalism. The generalized theory provides a method to compare the rotational barriers for different helices in lipid bilayers, accounting for long-range interactions via a parameter which is called "entropic index". The results obtained could lead to point out future experiments which might shed light on lipid-protein interactions. © 2004 Published by Elsevier B.V.
Description
Keywords
Chemistry, Physical , Lipid Bilayers , Membrane Proteins , Membrane Transport Proteins , Models, Chemical , Protein Structure, Secondary , Thermodynamics , lipid , article , bilayer membrane , lipid bilayer , mathematical computing , priority journal , protein lipid interaction , protein structure , rotation , theoretical study