Evaluation of the therapeutic use of antibiotics in Aegean Region hospitals of Turkey: A multicentric study

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dc.contributor.authorOzgenç O.
dc.contributor.authorGenç V.E.
dc.contributor.authorAri A.A.
dc.contributor.authorSibel E.L.
dc.contributor.authorSaçar S.
dc.contributor.authorOzunlu H.
dc.contributor.authorAkgul A.
dc.contributor.authorDemirturk N.
dc.contributor.authorÇetin C.B.
dc.contributor.authorSungur M.
dc.contributor.authorCoskuner S.A.
dc.contributor.authorAvci M.
dc.contributor.authorErgonul O.
dc.date.accessioned2024-07-22T08:20:32Z
dc.date.available2024-07-22T08:20:32Z
dc.date.issued2011
dc.description.abstractPurpose: The antibiotic restriction policy has been validated nationwide since February 2003 by the Ministry of Health because the excessive consumption of antimicrobials causes a high cost. The aim of this study was to evaluate the therapeutic use of antibiotics in Aegean Region hospitals and to assess the impact of this nationwide antibiotic restriction policy. This new policy is based on justification that the infectious disease (ID) physicians should be primarily responsible for the prescription of antimicrobials. Materials and Methods: Eight university and government hospitals were included in the study. The criteria of the Council for Appropriate and Rational Antibiotic Therapy (CARAT) were considered. Both patient-based and antibiotic-based analyses were performed. For the analysis of inappropriate use, logistic regression was modeled. Results: Therapeutic use was determined in 540 patients by a total of 29 ID physicians.In the study, 30.2% of the patients were given antimicrobials and empirically started antibiotics accounted for 79% cases of therapeutic antibiotic use, and 60% of those were inappropriate (P = 0.001). The appropriate use of ID level antibiotics (P = 0.000) were very compatible with other antimicrobial groups. Conclusion: The study shows that the Turkish government′s new intervention policy on antimicrobial prescribing has been effective.
dc.identifier.DOI-ID10.4103/0255-0857.81788
dc.identifier.issn02550857
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/18196
dc.language.isoEnglish
dc.publisherWolters Kluwer Medknow Publications
dc.subjectamikacin
dc.subjectamoxicillin
dc.subjectampicillin
dc.subjectantibiotic agent
dc.subjectcefazolin
dc.subjectcefoperazone
dc.subjectcefotaxime
dc.subjectcefprozil
dc.subjectceftazidime
dc.subjectceftizoxime
dc.subjectceftriaxone
dc.subjectcefuroxime
dc.subjectcilastatin
dc.subjectciprofloxacin
dc.subjectfluconazole
dc.subjectgentamicin
dc.subjectimipenem
dc.subjectitraconazole
dc.subjectlevofloxacin
dc.subjectmeropenem
dc.subjectmetronidazole
dc.subjectmoxifloxacin
dc.subjectnetilmicin
dc.subjectpenicillin G
dc.subjectpiperacillin
dc.subjectsulbactam
dc.subjecttazobactam
dc.subjectteicoplanin
dc.subjectadult
dc.subjectarticle
dc.subjectcross-sectional study
dc.subjectdrug screening
dc.subjectdrug use
dc.subjectfemale
dc.subjecthuman
dc.subjectinfection
dc.subjectmajor clinical study
dc.subjectmale
dc.subjectmulticenter study
dc.subjectphysician
dc.subjectprescription
dc.subjectTurkey (republic)
dc.titleEvaluation of the therapeutic use of antibiotics in Aegean Region hospitals of Turkey: A multicentric study
dc.typeArticle

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