Association of rhabdomyolysis and deep venous thrombosis as a rare complication of haloperidol treatment

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dc.contributor.authorErol A.
dc.contributor.authorKarataş S.
dc.date.accessioned2024-07-22T08:22:58Z
dc.date.available2024-07-22T08:22:58Z
dc.date.issued2007
dc.description.abstractBackground: Rhabdomyolysis is one of the reasons for acute renal failure. Deep vein thrombosis (DVT) refers to the formation of a thrombus within a deep vein, commonly in the thigh or calf. DVT may lead to pulmonary emboli that can be fatal. Haloperidol is an antipsychotic drug. It has a broad spectrum of side effects. There are examples of DVT and rhabdomyolysis associated with haloperidol use in literature. However, there is no case that reports these two complications together with use of haloperidol. Case Report: A 33 year old woman who was treated with haloperidol for her agitation and acute psychotic reaction had been admitted to University Hospital because of DVT, rhabdomyolysis and loss of consciousness. Elevations of serum creatine kinase, aspartat transaminase and lactate dehydrogenase concentrations were compatible with the diagnosis of the rhabdomyolysis. Physical findings of right leg swelling, warmth, erythema and tenderness; radiological finding of right femoral and inferior vein thrombosis at CT venography were consistent with DVT. All other reasons for these two conditions had been excluded in a long period of laboratory and clinical investigation. Conclusions: Along with the haloperidol therapy clinicians should be aware of rare complications like DVT and rhabdomyolysis. Patient, who was admitted to hospitals with rhabdomyolysis or DVT, should also be investigated about haloperidol use in differential diagnosis.
dc.identifier.issn16433742
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/19324
dc.language.isoEnglish
dc.subjectanticoagulant agent
dc.subjectaspartate aminotransferase
dc.subjectcreatine kinase
dc.subjecthaloperidol
dc.subjectlactate dehydrogenase
dc.subjectlow molecular weight heparin
dc.subjectacute kidney failure
dc.subjectadult
dc.subjectanamnesis
dc.subjectarticle
dc.subjectcase report
dc.subjectclinical feature
dc.subjectcomputer assisted tomography
dc.subjectdeep vein thrombosis
dc.subjectdisease association
dc.subjectdrug withdrawal
dc.subjectfemale
dc.subjecthuman
dc.subjecthypercoagulability
dc.subjectlung embolism
dc.subjectmental disease
dc.subjectphlebography
dc.subjectrhabdomyolysis
dc.subjecttomography
dc.titleAssociation of rhabdomyolysis and deep venous thrombosis as a rare complication of haloperidol treatment
dc.typeArticle

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