Evaluation of rational antibiotic use

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dc.contributor.authorTünger O.
dc.contributor.authorDinç G.
dc.contributor.authorÖzbakkaloglu B.
dc.contributor.authorAtman U.C.
dc.contributor.authorAlgün U.
dc.date.accessioned2024-07-22T08:25:38Z
dc.date.available2024-07-22T08:25:38Z
dc.date.issued2000
dc.description.abstractThe emergence of antibiotic resistant bacteria is a major problem throughout the world and a rational use of antibiotics is therefore very important. This study was performed to estimate the appropriateness of antimicrobial drug use in Celal Bayar University Hospital in Manisa. The data of all inpatients (n = 937) between October and December 1998 were collected according to the Kunin and Jones criteria. Of the patients, 16.6% (n = 156) were receiving antibiotics, and in 63.5, 23.0 and 13.5% of these, a single, two and three agents were used, respectively. The purpose of antibiotic use was for prophylaxis in 23.9%, as an empiric decision in 71.4% and for therapeutic culture-based reasons in 4.7%. The rate of rational antibiotic use was 45.7% and it was statistically higher in those patients from whom specimens had been taken for culture than in patients receiving prophylactic or empiric antibiotics. On medical wards, rational antibiotic usage was 55.1%, while it was 26.3% in surgical wards (P < 0.0001). The low rate of appropriate antibiotic use in our university hospital reflects the urgent need of rationalization. (C) 2000 Elsevier Science B.V. and International Society of Chemotherapy.
dc.identifier.DOI-ID10.1016/S0924-8579(00)00158-8
dc.identifier.issn09248579
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/20518
dc.language.isoEnglish
dc.subjectAnti-Bacterial Agents
dc.subjectBacterial Infections
dc.subjectCross-Sectional Studies
dc.subjectDrug Resistance, Microbial
dc.subjectDrug Utilization
dc.subjectFemale
dc.subjectHospitals, University
dc.subjectHumans
dc.subjectLength of Stay
dc.subjectMale
dc.subjectMiddle Aged
dc.subjectPharmacology, Clinical
dc.subjectTurkey
dc.subjectaminoglycoside antibiotic agent
dc.subjectbeta lactam antibiotic
dc.subjectbeta lactamase inhibitor
dc.subjectcarbapenem
dc.subjectcephalosporin derivative
dc.subjectglycopeptide
dc.subjectmacrolide
dc.subjectquinolone derivative
dc.subjectsulfonamide
dc.subjectadult
dc.subjectaged
dc.subjectantibiotic prophylaxis
dc.subjectantibiotic resistance
dc.subjectantibiotic therapy
dc.subjectarticle
dc.subjectfemale
dc.subjecthospital infection
dc.subjecthuman
dc.subjecthuman cell
dc.subjecthuman tissue
dc.subjectinfection
dc.subjectmajor clinical study
dc.subjectmale
dc.subjectpriority journal
dc.subjectsurgical technique
dc.subjectTurkey (republic)
dc.subjectuniversity hospital
dc.titleEvaluation of rational antibiotic use
dc.typeArticle

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