Araştırma Çıktıları | Web Of Science

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Investigation of the Effects of Moving Targets on Hit Force in Taekwondo
Kumartasli, M; Üncü, IS; Çatikkas, F; Akyüz, M; Kilim, O
The system to be developed has been designed in order to determine the training levels of the athletes in the field of taekwondo at national and international level and to follow-up the talent development process using computer support. The progression and continuity of hit power and time-dependent performance improvement of an athlete can be measured with interactive impact measurement system. The system determines a random target. It marks the target by blue light. When the light turns on, the athlete reacts accordingly and swiftly by kicking without knowing the light timing. The athlete only needs to know where the light is. Unlike in other training systems, the piston has been able to go back and forth in response to the strike of the athlete by means of a moving hydraulic system. The athlete can be pushed back by opening the piston when his/her performance drops down. The piston strike model is deactivated when the performance of the athlete is above a given threshold value. There will be four operating phases in the mechanism depending on the impact speed of the piston. Moving target robotic system analyses various hits in Taekwondo with the aim to determine hit force and reaction time. After completion of the warming up at the first stage, the athlete will be able to increase the workout level from low to high levels and will try to keep the mechanism behind as much as possible. Moreover, the athlete will be able to compare his/her results with results of others. Using this system, the efficiency of athletes can be easily determined and deficiencies can be resolved.
Chemoprotective effect of ascorbic acid, α-tocopherol, and selenium on cyclophosphamide-induced toxicity in the rat ovarium
Gürgen, SG; Erdogan, D; Elmas, Ç; Kaplanoglu, GT; Özer, Ç
Objective: The aim of the study was to evaluate the protective efficacy of ascorbic acid, alpha-tocopherol, and selenium by measuring the glutathione (GSH) levels and proliferating cell nuclear antigen (PCNA) and growth differentiation factor-9 (GDF-9) expression in the ovarian tissues of rats treated with cyclophosphamide (CP) therapy. Methods: Female Wistar rats were divided into 5 groups of 6 rats each: (I) control, (II) only CP, (III) CP + ascorbic acid, (IV) CP + alpha-tocopherol, and (V) CP + selenium. Immunohistochemical stainings and GSH protocol were then applied. Results: Following CP administration, the rats exhibited significantly lower GDF-9 expression in oocytes and PCNA expression in granulosa cells of follicles in all stages of development (P < 0.05). In CP + antioxidant groups (Groups III, IV, V), GDF-9 immunoreaction in oocytes and PCNA immunoreaction in granulosa cells of the developing follicles were found to show an increase towards the levels observed in the control group (P < 0.05). Conclusions: CP was found to cause remarkable degenerative effects in normal ovarian tissue, and we believe that this damage can be reduced and ovarian tissue can be spared from the toxic effects of CF by using antioxidants such as ascorbic acid, alpha-tocopherol, and selenium. (C) 2013 Elsevier Inc. All rights reserved.
Interactions between Salivary Proteins and Apple Polyphenols and the Fate of Complexes during Gastric Digestion
Kasikci, MB; Guilois-Dubois, S; Billet, K; Jardin, J; Guyot, S; Morzel, M
Beneficial polyphenols in apples can reach the stomach as complexes formed with salivary proteins. The present study aimed at documenting the interactions between salivary proteins and cider apple polyphenols and the fate of complexes during gastric digestion. A polyphenolic extract was mixed with human saliva, and interactions were characterized by analyzing proteins and polyphenols in the insoluble and soluble fractions of the mixtures, before and after in vitro gastric digestion. Results confirmed that proline-rich proteins can efficiently precipitate polyphenols and suggested that two zinc-binding proteins can also form insoluble complexes with polyphenols. The classes of polyphenols involved in such complexes depended on the polyphenol-to-protein ratio. In vitro gastric digestion led to extensive proteolysis of salivary proteins, and we formulate the hypothesis that the resulting peptides can interact with and precipitate some procyanidins. Saliva may therefore partly modulate the bioaccessibility of at least procyanidins in the gastric compartment.
Design and Finite Element Analysis of a 6/4 Pole Multi-Layer Fully Pitched Switched Reluctance Motor to Reduce Torque Ripple
Sahin, C; Basaran, S
-In this study, the design and analysis of multi-layer fully pitched winding switched reluctance motor (MFP-SRM) for general use (submersible pump, electric vehicles, etc.) have been performed. It is seen that the multi-layer switched reluctance motor (SRM) has higher output power when compared to the single-layer SRM. In multi-layer SRM, the motors in the layers are electromagnetically independent of each other although they are identically the same motors with the same characteristics in terms of performance and geometry. Each layer of the MFP-SRM which is designed in this study consists of a 6/4 pole fully pitched SRM (FP-SRM) and these motors are magnetically independent of each other. In the MFP-SRM, which is designed as a double layer, there is a 15 degrees phase difference between the rotor position angles and torque profile curves of each layer. With the phase difference that changes depending on the number of layers, each layer contributes to the total torque production of the profile, ensuring a smooth profile. According to the results of the 3D FEM analysis, it is seen that the proposed multi-layer motor structure has high starting torque and low torque ripple properties. In the analysis carried out in the range of 3-15 Amperes, the torque ripple of the traditional FP-SRM varies between 31.99% and 38.19%, while the torque ripple of the proposed MFP-SRM only varies between 3.23% and 7.11%.
Effects of Electric Discharge Plasma Treatment on the Thermal Conductivity of Polymer-Metal Nitride/Carbide Composites
Parali, L; Kurbanov, MA; Bayramov, AA; Tatardar, FN; Sultanakhmedova, RI; Xanlar, HG
High-density polymer composites with semiconductor or dielectric fillers such as aluminum nitride (AIN), aluminum oxide (Al2O3), titanium carbide (TiC), titanium nitride (TiN), boron nitride (BN), silicon nitride (Si3N4), and titanium carbonitride (TiCN) were prepared by the hot pressing method. Each powder phase of the composites was exposed to an electric discharge plasma process before composite formation. The effects of the electric discharge plasma process and the filler content (volume fraction) on the thermal conductivity, volt-ampere characteristics, thermally stimulated depolarization current, as well as electrical and mechanical strength were investigated. The results of the study indicate that, with increasing filler volume fraction, the thermal conductivity of the samples also increased. Furthermore, the thermal conductivity, and electrophysical and mechanical properties of the high-density polyethylene + 70% BN composite modified using the electric discharge plasma showed improvement when compared with that without electric discharge plasma treatment.
Large primary intraorbital hydatid cyst
Yurt, A; Seçer, M; Selçuki, M
The authors report a rare case of a large primary intraorbital hydatid cyst diagnosed in 3-year-old children who had presented with unilateral progressive nonpulsatile proptosis of the left eye, explored by computed tomography and magnetic resonance imaging.
Omalizumab in patients with severe persistent asthma in real life setting in Manisa, Turkey
Havlucu, Y; Yorgancioglu, A; Kurhan, F; Özdemir, L; Coskun, S; Goktalay, T; Yilmaz, O; Celik, P
Asymptomatic Giant Renal Calculi: Single-Session Percutaneous Nephrolithotomy-Images
Bozkurt, YE; Temeltas, G; Üçer, O; Müezzinoglu, T
In a 55-year-old woman patient with a body mass index of 27 kg/m(2), a giant staghorn kidney stone (10 x 6.4 x 8 cm) was detected in the right kidney on computed tomography, then the patient was treated with a single-session percutaneous nephrolithotomy, and there were no complications afterwards.
Humiliation Motif into The Dede Korkut Narratives
Kuzay Demir, G; Duranli, M
There are many common characteristic among the oral cultural products of nations all over the world. The differences and similarities between oral cultural products enable the appearence of motif oriented studies. There are many motifs around the world that have universal usage. One of them is the motif that emerges as being humiliated or humiliate which has a universal usage. Although it has so common usage, in Turkish Epopees any studies have not been done about the motif of being humiliated or humiliate until today. This situation that emerges as a result of searching for someone's disabilities and weaknesses within a community and causes a person to be excluded from the population, comprises one of the basic motifs that cause a series of actions to appear when it is the subject of epopee heroes in epical narrations. Epopees are the narratives of heroism that mention the success, unity and integrity of a society based on individual. In these works, ideal heroes who make a bid for society exist rather than the heroes coming into prominence with their human features. So, in epopees `being humiliated or humiliate of the hero is only possible when counter response appears. When it is used alone, humiliation which is identified as scorning or underrating, and has no contribution to progress of the narration can only be evaluated as a motif when it starts an action after itself. In this sense the humiliation motif is a feracious motif' and integrates with a variable motif that emerges after itself. In this article emphasis is put on humiliation motif in Dede Korkut narrations which is one of the important works of Turkish culture. First, the concept of word is identified and then it is discussed whether it could be a motif or not. Subsequently, the episodes that cause the humiliation motif in Dede Korkut narrations to appear and emerge as a result of this motif are determined, and a structural analysis is performed by considering the frequency of usage in narrations. In this study it is attempted to determine the usage of humiliation motif which is a universal motif through Dede Korkut narrations and the values highlighted in Turkish culture through motif is detected.
Effect of Subcutaneous Immunotherapy on The Natural Course of Allergic Diseases in Pediatric Patients: A Real-Life Cohort
Yilmaz, O; Yasar, A; Simsek, Y; Alpdogan, S; Kunay, B; Yuksel, H
Aim: Specific allergen immunotherapy (SIT) is the only disease-modifying therapy for allergic diseases. We aimed to examine the effect of subcutaneous specific allergen immunotherapy (SCIT) applications on the prognosis of asthma and allergic rhinitis in pediatric cases in real-life settings. Methods: The study was designed as a retrospective cohort study. Patients with asthma and/or allergic rhinitis aged between 5 and 18 years old were enrolled between 2010 and 2015. The groups who received SCIT and who did not receive were compared in terms of disease severity parameters in follow-up recorded in their files. Results: A total of 298 cases, among which 140 received subcutaneous specific allergen immunotherapy. The frequency of asthma, allergic rhinitis, and co-morbidity was similar between the two groups. In the first year of the follow-up, asthma symptoms severity was not significant between the two groups; however, both asthma and allergic rhinitis symptoms were significantly lower in the SCIT patients at the end of the third year of follow-up. While the follow-up rate for three years or more was 62% in the group that received subcutaneous specific allergen immunotherapy, it was 38% in the group that did not receive. Conclusion: These results showed that SIT is an effective treatment modality in real-life settings with low side effects in pediatric patients with uncontrolled asthma and allergic rhinitis despite medical treatment.
The acute effect of orlistat on endothelial function in young obese women
Sekuri, C; Tavli, T; Avsar, A; Sozcuer, H; Uyanik, BS; Ari, Z
Recent studies indicate that abdominal fat accumulation is related to impaired endothelial function in young healthy volunteers. The aim of this study was to determine the acute effect of gastrointestinal lipase inhibitor on brachial flow-mediated vasodilatation and hemodynamic parameters in young obese women. The study population was composed of 42 female obese patients (mean age 29 +/- 4 years, age range between 18 and 34 years). Flow-mediated endothelial-dependent vasodilatation was assessed in the brachial artery in response to reactive hyperemia using high-resolution ultrasound. Brachial artery diameter (3.46 +/- 0.72 mm to 3.82 +/- 0.84 mm) and flow-mediated vasodilation (7.6 +/- 0.8% to 9.8 +/- 1.6%) changed significantly after 12 weeks of therapy (p < 0.001). Brachial artery flow was not changed (124 +/- 92 ml/min to 148 +/- 14 ml/min, p > 0.05). The results of this study demonstrate that orlistat improved endothelial function, weight, body mass index and systolic and diastolic blood pressure in young women.
The impact of self-stigmatization on functioning in bipolar disorder
Aydemir, Ö
Objective: It has been shown that self-stigmatization causes low self-esteem and social anxiety in bipolar patients. In this study it is aimed to demonstrate the impact of self-stigmatization on psychosocial functioning in bipolar disorder. Method: The study was carried out with 70 patients diagnosed with bipolar disorder. All patients were in remission and the remission state was confirmed by a 17-item Hamilton Depression Rating Scale score less than 7 and a Young Mania Rating Scale score less than 5. For the assessment of self-stigmatization, sense of stigmatization subscale of Bipolar Disorder Functioning Questionnaire (BDFQ-Stigma) was used. In the assessment of functioning, Functioning Assessment Short Test (FAST) was applied which includes the dimensions such as autonomy, occupational functioning, cognitive functioning, financial issues, interpersonal relations, and leisure time. In the statistical analysis, regression analysis was performed. Results: In the regression analysis, R square was found to be 0.205 and the model was statistically significant (F=3.225, p=0.007). The only domain which is affected by self-stigmatization was found to be interpersonal relations (Beta=0.888, t=2.000, p<0.05). Conclusion: It is concluded that self-stigmatization has negative impact on interpersonal relations by causing social anxiety as demonstrated previously. On the other hand self stigmatization does not show any adverse effect on the other dimensions of FAST including occupational functionality.
Increasing production rate in U-type assembly lines with sequence-dependent set-up times
Sahin, M; Kellegöz, T
U-shaped assembly lines are commonly used in just-in-time production systems as they have some advantages over straight lines. Although maximizing production rates on these lines by assigning tasks to stations is common practice in industrial environments, studies on the stated assembly line balancing problem are limited. This article deals with maximizing the production rate on U-shaped assembly lines under sequence-dependent set-up times. Sequence-dependent set-up times mean that after a task is performed, a set-up time, the duration of which depends on adjacent tasks, is required to start the next task operation. These set-ups are considered by dividing them into two groups, named forward and backward set-ups, to make the problem more practical. Two heuristics based on simulated annealing and genetic algorithms are improved beside the mathematical model. Experimental results show that solving the stated problem using the mathematical model is nearly impossible, while heuristics may obtain solutions that have acceptable deviations from the lower bounds.
Mechanical and fluoride release properties of titanium tetrafluoride-added glass-ionomer cement
Pamir, T; Sen, BH; Celik, A
The aim of this study was to determine the fluoride-release and mechanical properties of a water-hardening glass-ionomer cement (GIC) (ChemFil Superior) when titanium tetrafluoride (TiF4) was added. Three experimental groups were prepared with TiF4 added to the liquid component of the material in concentrations of 0.5, 1, and 2%. The control group was the original form of the cement and free of TiF4. After the specimens (4 nun in diameter X 6 mm in length) were prepared, their compressive strength, microhardness, modulus of elasticity, and fluoride release were measured. Data were analyzed using one-way analysis of variance (ANOVA) and post-hoc test (Bonferroni/Dunn correction). The addition of TiF4 into GIC significantly reduced fluoride release from the material with the exception of 1% TiF4 (p < 0.0083). Compressive strengths of 0.5 and 1% TiF4-added GICs were higher than that of the original GIC, but it was not statistically significant (p > 0.05). The differences among modulus of elasticity values of experimental and control groups were not significant (p > 0.05). Similarly, microhardness of GIC was not affected with TiF4 addition (p > 0.05).
Reliability and validity of Turkish Form of DSM-5 Self-Rated Level 1 Cross-Cutting Symptom Scale-Adult Version
Çökmüs, FP; Balikçi, K; Aydemir, O
Objective: The aim of this study is to demonstrate the reliability and validity of the Turkish Form of DSM-5 SelfRated Level 1 Cross-Cutting Symptom Scale Adult Version which is developed according to DSM-5 criteria to measure the severity of general symptomatology. Methods: This research was carried out with patients and their relatives who fulfilled the criteria of any psychiatric disorder according to DSM-5 criteria in inpatient and outpatient psychiatric clinics of Manisa Celal Bayar University, School of Medicine and healthy control group without any mental or physical disease. Accordingly, the distribution of psychiatric diagnosis of the patients were as follows: 39 patients with major depressive disorder, three patients with panic disorder, two patients with obsessive-compulsive disorder, four patients with schizophrenia, two patients with schizoaffective disorder, seven patients with BTA anxiety disorder, two patients with conversion disorder and post-traumatic stress disorder in one patient. Beside Level 1 Cross-Cutting Symptom Scale, the most widely used for general semptomatology self-rated scale, Symptom Check List-90-Revised Form (SCL-90-R) was used for concurrent validity. In reliability analysis internal consistency coefficient and item-total correlation analysis; in validity analyses exploratory factor analysis and correlation analysis with the SCL-90-R and subscales was performed for validation. Results: This research was carried out with 206 volunteers. 61.2% of the sample group (n= 126) were female and the mean age of the study group was 35.1 +/- 11.2 years. 29.6% of the group were college graduates, 36.4% primary school graduates, 7.8% middle school graduates and 23.3% were also high school. The internal consistency of the Level 1 Cross-Cutting Symptom Scale was 0.94 and, item-total score correlation coefficients of the Level 1 Cross-Cutting Symptom Scale were between 0.30-0.79. In the exploratory factor analysis, for sample adequacy Kaiser-Meier-Olkin (KMO) coefficient was calculated as 0.92 and Bartlett coefficient was 3007.76. Three-factor solution was obtained, representing 60.8% of the total variance. In the analysis of the correlation between the subscales of SCL-90-R and subscales of the Level 1 CrossCutting Symptom Scale were as follows; for depression r= 0.72, for anxiety r= 0.80, for somatization r= 0.72, for psychosis r= 0.70, for obsessive compulsive symptoms r= 0.68, for personality r= 0.72, for suicide r= 0.53, for sleep r= 0.76, for anger r= 0.64 and for the total score r= 0.87 was obtained. Conclusion: These findings show that the Level 1 Cross-Cutting Symptom Scale is reliable and valid for Turkish.
A Comparison of Smokers, Non-Smokers, and Those Undergoing Treatment in Terms of Attitudes on Coping with Stress and Psychological Resilience
Acar, S; Kayli, DS; Yararbas, G
This study compares the attitudes on resilience and coping with stress of smokers, non-smokers, and those undergoing smoking-cessation treatment. This study involves three study groups: 116 people who applied to the Institute on Drug Abuse, Toxicology, and Pharmaceutical Science Smoking Cessation Polyclinic in Ege university to stop smoking, 110 smokers, and 121 non-smokers. The individual information form has been prepared in order to measure the variables of gender, age, and education level. In addition to the individual information form, the Fagerstrom Test for Nicotine Dependence, the Brief Coping Styles Inventory (Brief COPE), and the Resilience Scale for Adults have been used. The Kruskal-Wallis and Mann-Whimey U tests have been utilized in addition to descriptive statistics in analyzing the obtained data. Based on multiple comparisons among the three groups, significant differences among the groups have been obtained in certain sub-dimensions for the variables in coping strategies and resilience, as well as significant differences between smokers and the other groups in terms of their levels of resilience.
Long term efficacy of fixed-dose omalizumab for patients with severe chronic urticaria
Havlucu, Y; Yorgancioglu, A; Havlucu, DY; Madak, B; Kurhan, F
The validity and reliability of the Turkish version of the Leicester Cough Questionnaire in COPD patients
Kurhan, F; Göktalay, T; Havlucu, Y; Sari, S; Yorgancioglu, A; Çelik, P; Coskun, AS
Background/aim: The reliability and validity of the Turkish version of the Leicester Cough Questionnaire (LCQ) have been evaluated before. This study aimed to validate the Turkish version of the LCQ in chronic obstructive puhnonary disease (COPD) patients with cough. Materials and methods: COPD (GOLD B, C, D) patients over age 40 (n = 75) and healthy volunteers as a control group (n = 75) were included. A sociodeinographic data form, the LCQ, the Short Form-36 (SF-36) quality of life questionnaire, and the World Health Organization Quality of Life Brief Form for Turkish people were completed. The internal reliability of the LCQ was determined using the Cronbach alpha coefficient (>0.6) and its repeatability by the intraclass consistency coefficient (P < 0.05) was accepted as significant. Results: For internal consistency, Cronbach alpha coefficients of all subscales of the LCQ, physical, psychological, and social, were found as 0.72, 0.86, and 0.83, respectively, with 0.92 for the total index. There was significant internal consistency for all subscales and the total index (Cronbach alpha coefficients of >0.6). In test-retest reliability, the correlation coefficient ranged between 0.71 and 0.80 for each question and was calculated as r = 0.89 for total LCQ score (P < 0.001). Conclusion: The Turkish version of the LCQ has been found to have acceptable reliability and validity for use in Turkish COPD patients with chronic cough.
DESCRIPTION OF THE UNKNOWN FEMALE OF THE HARVESTMAN RAFALSKIA AZIZSANCARI KURT, YAGMUR & TEZCAN, 2019 (ARACHNIDA: OPILIONES: PHALANGIIDAE) FROM TURKEY
Kurt, K; Yagmur, EA; Kurt, P
The female of Rafalskia azizsancari Kurt, Yagmur & Tezcan, 2019, previously known only from the male in Turkey, is now described based on new material from Odemis District, Izmir Province, Turkey. Detailed morphological descriptions, photographs and illustration of the female ovipositor are provided.
Comparison of the protective effects of intratympanic dexamethasone and methylprednisolone against cisplatin-induced ototoxicity
Özel, HE; Özdogan, F; Gürgen, SG; Esen, E; Genç, S; Selçuk, A
Objective: This study aimed to compare the efficacies of intratympanic dexamethasone and methylprednisolone in preventing in cisplatin-induced ototoxicity in rats. Methods: Experimental groups of rats (n = 8 each) received intratympanic isotonic saline, intraperitoneal cisplatin and intratympanic isotonic saline, intraperitoneal cisplatin and intratympanic dexamethasone, or intraperitoneal cisplatin and intratympanic methylprednisolone. Distortion product otoacoustic emission thresholds were compared on days 0 and 10 in all rats, and correlations between drug effects and changes in cochlear histology were evaluated. Results: Distortion product otoacoustic emission thresholds were comparable in groups III and IV (p > 0.05). Significant protection against cisplatin-induced ototoxicity was seen in groups III and IV compared with group II (p < 0.05). Dexamethasone and, to a lesser extent, methylprednisolone protected against cellular apoptosis in cisplatin-induced ototoxicity. Conclusion: Dexamethasone (and possibly methylprednisolone) may be clinically useful as an intratympanic chemopreventive agent to treat cisplatin ototoxicity. Future clinical studies should investigate the use of dexamethasone for this purpose in adult patients.

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