Browsing by Subject "red alga"
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Item The cytotoxic, neurotoxic, apoptotic and antiproliferative activities of extracts of some marine algae on the MCF-7 cell line(Informa Healthcare, 2014) Kurt O.; Özdal-Kurt F.; Tuʇlu M.I.; Akçora C.M.We investigated the cytotoxic, neurotoxic, apoptotic and antiproliferative effects of extracts from Petalonia fascia, Jania longifurca and Halimeda tuna on the MCF-7 breast cancer cell line. J. longifurca extracts were more toxic than those of P. fascia and H. tuna. The algal extracts showed significant toxic effects at different dilutions. The toxic effects were due to increased oxidative stress and resulted in apoptosis. Algal toxicity may exert negative effects through the food chain or by direct interaction. Algal toxicity also has potential for cancer therapy. The toxic effects that we observed may be especially important for therapy for breast tumors. © 2014 The Biological Stain Commission.Item First report of the red alga Gayliella fimbriata in the Mediterranean Sea(Walter de Gruyter GmbH, 2015) Taşkln E.; Çaklr M.; Wynne M.J.The red alga Gayliella fimbriata (Ceramiaceae, Rhodophyta) is reported for the first time from the Mediterranean Sea. This species was collected growing as an epiphyte on Laurencia obtusa in the sublittoral zone at Antalya (Mediterranean coast of Turkey). Gayliella fimbriata is characterized by its protruding clavate gland cells. Features to distinguish the four Turkish species of Gayliella from one another are provided. © 2015 by De Gruyter 2015.Item Anti-acetylcholinesterase, antiprotozoal and cytotoxic activities of some Turkish marine algae(Parlar Scientific Publications, 2019) Cinar E.; Taskin E.; Tasdemir D.; Ozkale E.; Grienke U.; Firsova D.The crude (MeOH:CHCl3) and n-hexane-soluble extracts from four brown algae (Phaeophyceae) [Petalonia fascia, Cystoseira crinita, Cystoseira foeniculacea, and Halopteris scoparia], one red alga (Rhodophyta) [Jania rubens] and three green algae (Chlorophyta) [Chaetomorpha aerea, Codium fragile subsp. fragile, and Ulva compressa] from Turkish coasts (Izmir Bay, Ayvalik and Çanakkale) were assessed in vitro for their acetylcholinesterase (AChE) inhibitory activities at 200, 150, 50, 20 μg/mL test concentration with Ellman's method. The crude extract of P. fascia possessed the highest inhibition (IC5 0 value of 19,22±10,47 μg/mL) against AChE. Galanthamine HBr was used as standard drug that gave against AChE enzyme IC5 0 of 3.44±1.14 μM. In the second stage, the crude, hexane-soluble, chloroform-soluble and water-methanol soluble extracts of the marine algae were observed in vitro against parasitic protozoa (Plasmodium falciparum, Trypanosoma brucei brucei, Trypanosoma cruzi ve Leishmania infantum). According to results, the most potent protozoal activities were shown by the Khex of C. crinita (IC5 0 value of 10,62 μg/ml), followed by the Khex of C. fragile subsp. fragile (IC50 value of 11,89 μg/ml). The hekzan-soluble (Khex) and chloroform-soluble (KCH) extracts gave the best results. The marine algae were also tested on MRC-5 cells (human fibroblasts) for by controlling tamoxifen. The extracts of H. scoparia, C. aerea ve C. fragile subsp. fragile showed toxicity. © by PSP