Browsing by Subject "spectral domain optical coherence tomography"

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    Evaluation of macula with optical coherence tomography in patients with decreased visual acuity after successful retinal detachment surgery; [Başarılı Regmatojen Retina Dekolmanı Ameliyatlarından Sonra Görme Rehabilitasyonunun Saǧlanamadıǧı Olgularda Makulanın Optik Koherens Tomografi ile Deǧerlendirilmesi]
    (Turkish Ophthalmology Society, 2012) Seymenoǧlu G.; Şahin B.Ö.; Top C.G.; Kayikçioǧlu O.; Başer E.
    Purpose: To study the foveal microstructural changes that may explain the incomplete visual recovery in eyes with anatomically successful repair of rhegmatogenous retinal detachments (RRD) using spectral-domain optical coherence tomography (OCT) and to evaluate the correlation between foveal changes and postoperative visual acuity. Material and Method: Forty-four eyes of 43 patients with macula-off RRDs were examined in our study. Patients were examined on first, third and sixth months postoperatively. The patients had a complete ophthalmological examination and OCT images were obtained at all postoperative visits. The postoperative OCT findings were classified in 4 groups: Group 1: continuous inner segment/outer segment (IS/OS) line, Group 2: disrupted IS/OS line, Group 3: epiretinal membrane (ERM), Group 4: residual foveal detachment. Results: Postoperative OCT findings showed that group 1 consisted of 19 eyes (43.2%), group 2 consisted of 15 eyes (34.1%), group 3 consisted of 7 eyes (15.9%) and group 4 consisted of 3 eyes (6.8%). The mean best-corrected visual acuity (BCVA) was significantly higher (p<0.001). Discussion: Spectral-domain OCT provides valuable information which helps the understanding of foveal microstructural changes and explains the possible causes of poor postoperative visual acuity in eyes with anatomically successful RRD repair.
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    Comparison of spectral-domain optical coherence tomography and heidelberg retina tomograph III optic nerve head parameters in glaucoma
    (2013) Seymenoǧlu G.; Başer E.; Öztürk B.
    Background: To evaluate the agreement between the optic nerve head (ONH) measurements obtained by spectral-domain optical coherence tomography/scanning laser ophthalmoscope (SD-OCT/SLO) and the Heidelberg retinal tomograph III (HRT-III), and to compare the ONH measurements of both devices in different glaucoma types. Methods: In a prospective study, 30 patients with primary open-angle glaucoma (POAG) and 30 patients with pseudoexfoliation glaucoma (PXG) were enrolled. All patients underwent SD-OCT/SLO and HRT-III evaluation of the ONH during the same visit. Agreement between measurements of SD-OCT/SLO and HRT-III were evaluated by determination of intraclass correlation coeficients. In addition, mean ONH measurements obtained with both devices were compared between POAG and PXG patient groups. Results: Mean SD-OCT/SLO measurements were greater than those of HRT-III, except for mean and maximum cup depth. Intraclass correlation coefficient values for disc area, rim area, cup area, cup/disc area ratio, mean cup depth and maximum cup depth were 0.367, 0.213, 0.632, 0.681, 0.775 and 0.661, respectively. No significant differences were found between ONH parameters of POAG and PXG patients as measured with both devices (p > 0.01). Conclusion: ONH measurements with SD-OCT/SLO and HRT-III did not show clinically acceptable agreement in glaucoma patients. This precludes interchangeable use of these measurements in clinical practice. PXG and POAG patient groups displayed similar ONH measurements with both devices. Copyright © 2012 S. Karger AG, Basel.
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    Should we worry about the eyes of celiac patients?
    (SAGE Publications Ltd, 2020) Doğan G.; Şen S.; Çavdar E.; Mayalı H.; Cengiz Özyurt B.; Kurt E.; Kasırga E.
    Purpose: In this article, we evaluate subfoveal choroidal thickness in celiac patients with respect to adherence to the gluten-free diet and nonadherence to the gluten-free diet, comparing with age and sex matched healthy controls using spectral-domain optical coherence tomography. Materials and Methods: A case-control study among 42 celiac patients and 42 healthy participants was conducted in the Department of Pediatric Gastroenterology. Celiac patients of our policlinics compliant with spectral-domain optical coherence tomography examination enrolled in the study. Celiac patients had been asked verbally about their adherence to gluten-free diet, were evaluated according to negative or positive EmA and anti-TG2 for defining adherence, and were divided into two groups (adherence to gluten-free diet and nonadherence to gluten-free diet). Results: Subfoveal choroidal thickness was thinner in EmA (+) or anti-TG2 (+) eyes than EmA(−) or anti-TG2 (−) eyes in celiac patients, but it was not statistically significant. The mean subfoveal choroidal thickness values in eyes with celiac disease, whose diagnosis time was longer than 60 months, were thinner than shorter group. Longer duration of gluten-free diet was associated with adherence difficulty and thinner choroidal thickness (r = −0.15, p = 0.34). Adherence to gluten-free diet was 88.2% for children below the age of 60 months and 57.1% for children older than 60 months. Conclusion: In conclusion, in addition to other extraintestinal manifestations of celiac disease, diagnosis time longer than 60 months in pediatric celiac patients, nonadherence to the gluten-free diet, and antibody positivity should be focused on during ophthalmologic examination and choroid measurement. © The Author(s) 2019.
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    Efficacy of topical brinzolamide treatment in posterior microphthalmos-related macular cystoid lesions: A case series
    (Turkish Ophthalmology Society, 2020) Engin C.D.; Ekinci U.B.; Selver A.; Saatçi A.O.
    The aim of this study was to report the outcome of topical brinzolamide 1% treatment on macular cystoid lesions resembling retinoschisis in 4 patients diagnosed with posterior microphthalmia. The medical records of 4 patients with a clinical diagnosis of posterior microphthalmia who had started topical brinzolamide 1% treatment were reviewed. Visual acuity, central foveal thickness, and cystoid lesion area percentage were used to evaluate treatment response. In the follow-up, there was a decrease in central foveal thicknesses and cystoid lesion area percentages in both eyes of 3 of the patients. However, 1 patient showed increases in both parameters. Visual acuity remained stable in 5 eyes and increased in 3 eyes. Topical brinzolamide treatment may have some positive effects on macular cystoid lesions in selected cases. © 2020 by Turkish Ophthalmological Association Turkish Journal of Ophthalmology, published by Galenos Publishing House.
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    Multimodal ocular evaluation in hemodialysis patients
    (Springer Science and Business Media B.V., 2021) Mayali H.; Altinisik M.; Sarigul C.; Toraman A.; Turkoglu M.S.; Kurt E.
    Purpose: To evaluate choroidal thickness, intraocular pressure (IOP), axial length, central corneal thickness (CCT), lens thickness, anterior chamber depth, and ocular pulse amplitude (OPA) in hemodialysis patients. Materials and methods: The patients with end-stage renal disease and undergoing hemodialysis were included in the study. Immediately before and 1 hour after hemodialysis, all patients underwent measurement of choroidal thickness with spectral domain optical coherence tomography (SD-OC, Cirrus HD-OCT; Carl Zeiss Meditec Inc., Dublin, CA), IOP and OPA with Pascal dynamic contour tonometry (Ziemer Ophthalmic Systems AG, Port, Switzerland), and anterior chamber depth, lens thickness, and axial length with optical biometry (LenStar LS900; Haag-Streit AG, Koeniz, Switzerland). Data from the patients’ right eyes were included in the statistical analysis. Results: The patient group included 8 (36.4%) males and 14 (63.6%) females with a mean age of 56, 14 ± 9, 96 (40–70) years. The mean subfoveal choroidal thickness before and after hemodialysis was 255.21 ± 6.15 (245–263) µm and 234.95 ± 7.89 (220–247) µm, respectively (p < 0.001). Mean choroidal thickness at 1500 µm and 3000 µm nasal and temporal of the fovea also decreased significantly after hemodialysis (p < 0.001). Mean OPA values before and after hemodialysis were 2.14 ± 1.07 (0.6–4) mmHg and 1.6 ± 0.86 (0.5–3.2) mmHg, respectively (p < 0.001). There was a statistically significant correlation between OPA and choroidal thickness measurements (p < 0.001, R = 0.923). IOP increased from 15.11 ± 2.58 (11–20) to 15.99 ± 2.21 (13–20) mmHg, but the change did not reach statistical significance (p = 0.05). There was no statistically significant change in mean axial length, anterior chamber depth, lens thickness, or CCT after hemodialysis (p > 0.05 for all). Conclusion: Although choroidal thickness and OPA may be decreased immediately after hemodialysis, there may be no significant changes in IOP or avascular ocular structures such as the lens and cornea. © 2021, The Author(s), under exclusive licence to Springer Nature B.V.
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    A comparative study of type 1 neovascularization: Neovascular age-related macular degeneration versus pachychoroid neovasculopathy
    (SAGE Publications Ltd, 2022) Altinisik M.; Kurt E.; Sonmezer P.; Kayikcioglu O.; Ilker S.S.
    Purpose: This study aimed to compare type 1 choroidal neovascularization (CNV) characteristics in eyes with pachychoroid neovasculopathy (PNV) and neovascular age-related macular degeneration (nAMD) using optical coherence tomography angiography (OCTA). Methods: Treatment naive 23 eyes of 23 patients with PNV and 24 eyes of 24 patients with nAMD were evaluated. The height of pigment epithelial detachment (PED) and the central macular thickness were determined. OCTA sensitivity, CNV area, morphological patterns, and retinal superficial capillary plexus vessel density (SCP-VD) values were compared. The frequency of quiescent CNV, subretinal hyperreflective exudation (SHE), subretinal/intraretinal fluid, serous PED, double-layer sign (DLS), and pachyvessels were noted. Results: CNV was detected on OCTA in 83.3% of nAMD eyes and 91.3% of PNV eyes (p = 0.66). Indistinct pattern was more common (74% vs 50%) and the CNV area (mm2) was smaller in PNV (0.77 ± 0.54 vs 1.57 ± 1.43) but did not reach significant levels (p = 0.27 and 0.33 respectively). SCP-VD was similar between the groups (p = 0.38). Statistically significant differences were found between groups in age and subfoveal choroidal thickness (p < 0.05). DLS and pachyvessels were found to be more frequently in PNV (p < 0.05). However, both groups had similar rates of quiescent CNV, SHE, subretinal/intraretinal fluid, and serous PED (p > 0.05). Conclusion: Morphological features, area, and activation findings of type 1 CNV may play a limited role in differentiating nAMD and PNV cases. © The Author(s) 2021.
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    Short-term results of surgical treatment in large idiopathic macular hole cases
    (Springer Science and Business Media B.V., 2024) Doğruya S.; Karabacak D.D.; Altınışık M.; Delibay Y.; Kayıkçıoğlu O.C.; Kayıkçıoğlu Ö.R.
    Purpose: To evaluate results of the surgical treatment for large stage (Stage 3 and 4) idiopathic macular hole cases with and without ILM flap technique. Methods: Sixty eyes of 60 patients diagnosed with idiopathic macular hole (MH) were included in the study. Complete ophthalmologic examination and SD-OCT examination were performed in all eyes. MH stages, MH base diameter, height and closest distance were measured quantitatively. Postoperative and 3 months visits were evaluated. Results: The mean age of the cases was 65.0 ± 8.0 (range 30–84) years, there were 31 (51.7%) female and 29 (48.3%) male patients with a mean follow-up period of 18.1 ± 16.7 (range 3–63) months. The mean best corrected visual acuity recorded at preoperative and third month control visits were 0.89 ± 0.40(preoperative) logMAR, 0.82 ± 0.60(3 month) logMAR (p < 0.05). The mean MH index was 0.48 ± 0.16, the closest hole distance was 517.86 ± 210.89 µm and mean basal diameter of holes was 947.78 ± 361.90 µm and the average height was 448.93 ± 79.80 microns. There was no statistically significant difference between anatomic results of macular hole surgery with (n = 22) and without (n = 38) flap in terms of hole closure (86.4% vs. 92.1% p > 0.05). In 90% (54 cases) of the cases, closure was observed after the first surgery. Two eyes that failed macular hole surgery were reoperated. In one of these eyes, anatomical success was obtained with macular hole massage and mechanical cytumulation. However, anatomical success could not be achieved in the other eye. Conclusıon: In the treatment of large macular holes, pars plana vitrectomy, internal limiting membrane peeling with/without flap and gas tamponade demonstrated high anatomical and functional success. © The Author(s), under exclusive licence to Springer Nature B.V. 2024.