Venous thromboembolism prophylaxis in major orthopaedic surgery: A multicenter, prospective, observational study

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dc.contributor.authorAltintas, F
dc.contributor.authorGürbüz, H
dc.contributor.authorErdemli, B
dc.contributor.authorAtilla, B
dc.contributor.authorUstaoglu, RG
dc.contributor.authorÖziç, U
dc.contributor.authorSavk, O
dc.contributor.authorBayram, H
dc.contributor.authorMemik, R
dc.contributor.authorAkgün, I
dc.contributor.authorGögüs, A
dc.contributor.authorPestilci, F
dc.contributor.authorKonal, A
dc.contributor.authorArgün, M
dc.contributor.authorÖztürk, I
dc.contributor.authorDabak, N
dc.contributor.authorBilgen, OF
dc.contributor.authorSerin, E
dc.contributor.authorÖnder, Ç
dc.contributor.authorSimsek, A
dc.contributor.authorTözün, R
dc.contributor.authorKinik, H
dc.date.accessioned2024-07-18T12:08:06Z
dc.date.available2024-07-18T12:08:06Z
dc.description.abstractObjectives: We investigated risk factors for venous thromboembolism (VTE), prophylaxis measures employed, and incidence of symptomatic deep venous thrombosis (DVT) and pulmonary embolism (PE) in patients undergoing major orthopaedic surgery (MOS). Methods: An open, multicenter, prospective, observational study was conducted in 21 medical centers, comprising 899 patients. Of these. 316 patients (35.2%) underwent total hip arthroplasty (THA), 328 patients (36.5%) underwent total knee arthroplasty (TKA), and 255 patients (28.4%) underwent surgery for hip fractures (HF). Pharmacologic prophylaxis was employed in all the patients. Results: Risk factors for VTE were seen in 73.2% of the patents. the most common being obesity (72%) and prolonged immobilization (36.3%). Low-molecular-weight heparin (91.1%) and fondaparinux (8.9%) were used for prophylaxis, which was short-term in 273 patients (30.4%) and long-term in 626 patients (69.6%). Mechanical prophylaxis was performed with compression stockings in 610 patients (67.9%) and by intermittent pneumatic compression in 67 patients (7.5%). During three-months of follow-up, symptomatic DVT and PE were seen in eight (0.9%) and four patients (0.4%), respectively. Mortality occurred in 10 patients (1.1%). Complications of major and minor bleeding were seen in eight (0.9%) and 40 (4.5%) patients, respectively. Conclusion: Effective VTE prophylaxis is associated with low risk of clinically apparent DVT and PE in MOS.
dc.identifier.issn1017-995X
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/10781
dc.language.isoTurkish
dc.publisherTURKISH ASSOC ORTHOPAEDICS TRAUMATOLOGY
dc.subjectDEEP-VEIN THROMBOSIS
dc.subjectTOTAL HIP-ARTHROPLASTY
dc.subjectKNEE REPLACEMENT
dc.subjectRISK-FACTORS
dc.subjectPREVENTION
dc.subjectENOXAPARIN
dc.subjectDISCHARGE
dc.subjectHEPARIN
dc.subjectPLACEBO
dc.subjectDISEASE
dc.titleVenous thromboembolism prophylaxis in major orthopaedic surgery: A multicenter, prospective, observational study
dc.typeArticle

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