Toll-Like Receptor 2 Expression and Peripheral Blood CD4+/CD8+ T Cell Ratio in COPD

Simple item page
dc.contributor.authorFATMA TANELİ
dc.contributor.authorYEŞİM GÜVENÇ DEMİRAĞCI
dc.contributor.authorCemile ÇETİNKAYA
dc.contributor.authorCevval Ulman
dc.contributor.authorAYŞIN ŞAKAR COŞKUN
dc.contributor.authorGönül DİNÇ HORASAN
dc.contributor.authorGürol Şahin ULUTAŞ
dc.contributor.authorAylin ÖZGEN ALPAYDIN
dc.date.accessioned2025-04-14T05:50:16Z
dc.date.available2025-04-14T05:50:16Z
dc.date.issued2014
dc.description.abstractAs well as the relationship of these cells with pulmonary functions in chronic obstructive pulmonary disease (COPD) patients.MATerIAL ANd MeTHods: Forty COPD patients and 40 healthy volunteers were included. Participants were analysed in four groups according to their smoking status. Peripheral blood CD4+ and CD8+ T cells and monocyte TLR-2 expression were measured by flow cytometry in the whole study population.resULTs: No significant difference was observed in TLR-2 expression, number of CD4+ and CD8+ T cells, and CD4+/CD8+ T cell ratio between the study groups. CD4+/CD8+ T cell ratio and FEV1/FVC were found to have a mild positive correlation (r=0.295, p=0.022). A mild negative correlation was observed between smoking intensity and CD4+/CD8+ T cell ratio (r=-0.274, p=0.034).CoNCLUsIoN: We demonstrated a mild correlation between pulmonary functions and peripheral blood CD4+/CD8+ T cell ratio. However, we did not find a significant difference in TLR-2 expression of CD14+ monocytes in patients with airway obstruction.
dc.identifier.urihttp://hdl.handle.net/20.500.14701/53750
dc.language.isoİngilizce
dc.subjectSolunum Sistemi
dc.subjectGenel ve Dahili Tıp
dc.subjectİmmünoloji
dc.titleToll-Like Receptor 2 Expression and Peripheral Blood CD4+/CD8+ T Cell Ratio in COPD

Files

Collections

TR-Dizin Koleksiyonu