Asthma phenotypes in Turkey: a multicenter cross-sectional study in adult asthmatics; PHENOTURK study

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dc.contributor.authorYildiz F.
dc.contributor.authorMungan D.
dc.contributor.authorGemicioglu B.
dc.contributor.authorYorgancioglu A.
dc.contributor.authorDursun B.
dc.contributor.authorOner Erkekol F.
dc.contributor.authorOgus C.
dc.contributor.authorTurktas H.
dc.contributor.authorBogatekin G.
dc.contributor.authorTopcu F.
dc.contributor.authorDeveci F.
dc.contributor.authorBayram H.
dc.contributor.authorTor M.
dc.contributor.authorKalyoncu A.F.
dc.date.accessioned2025-04-10T11:08:43Z
dc.date.available2025-04-10T11:08:43Z
dc.date.issued2017
dc.description.abstractBackground and Aims: To evaluate asthma phenotypes in patients with asthma from different regions of Turkey. Methods: A total of 1400 adult asthmatic patients (mean (SD) age: 44.0 (13.9) years, 75% females) from 14 centers across Turkey were included in this study and a standard questionnaire was applied between the time period of February 2011–January 2012. Results: The disease onset ≥ 40 years of age was higher percentage in obese vs. normal/overweight patients and nonallergic vs. allergic patients (P < 0.01). The percentage of patients who had FEV1 values over 80% was higher in allergic than nonallergic and normal/overweight than obese patients (P < 0.01). Uncontrolled asthmatics have more severe disease (P < 0.01). There were more frequent hospital admissions in nonallergic and uncontrolled asthmatics (P < 0.01). Chronic rhino-sinusitis was the leading comorbid disorder in normal/overweight and allergic asthma, while gastroesophageal reflux disorder was more frequent in nonallergic and uncontrolled asthma (P < 0.01). Asthma control rate was the highest (39.0%) in patients from Marmara region among all geographical regions (P < 0.05). Conclusion: In conclusion, our findings revealed existence of clinical/trigger related phenotypes based on BMI, allergic status, control level and geographical region with more frequent respiratory dysfunction and/or adverse health outcomes in uncontrolled, obese and nonallergic phenotypes. © 2015 John Wiley & Sons Ltd
dc.identifier.DOI-ID10.1111/crj.12326
dc.identifier.urihttp://hdl.handle.net/20.500.14701/48229
dc.publisherBlackwell Publishing Ltd
dc.titleAsthma phenotypes in Turkey: a multicenter cross-sectional study in adult asthmatics; PHENOTURK study
dc.typeArticle

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