Clinical Features of Patients with Chronic Urticaria and the Results of the Skin Prick Tests
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Date
2019
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Abstract
Objective: Chronic urticaria (CU), which is mostly idiopathic, may also be a sign of an allergic or systemic disease. A variety of diseases andallergens that accompany CU have been reported in various studies. The aim of this study was to investigate the factors that play a role in theetiology of CU.Materials and Methods: The demographic and clinical data from 302 patients – aged over 18 years - who were being monitored for CU wererecorded. Several tests were performed to analyze comorbidities such as infection, malignancy, and autoimmune and rheumatic diseases. SkinPrick Test (SPT) results and questionnaires were reviewed.Results: Two hundred and thirteen out of the 302 patients with a mean age of 40.26±14.3 years were females. The duration of CU was 43.30±62.60months and 42.9% of the patients had comorbidities. The most common disease was autoimmune thyroiditis (13.9%). Fifty-five percent of thepatients were sensitive to inhalant allergens, and 5% exhibited allergen positivity for food. The most common allergens were house (43.7%) dustmites. Allergen positivity was 37.2% in those with comorbidities, while it was 62.8% in those without any comorbidities and this relationshipwas statistically significant (p<0.05).Conclusion: This study showed that there was an association between house dust mite and CU dust sensitivity. House dust mite sensitivity maytrigger CU.