Samarium-153 therapy for prostate cancer: The evaluation of urine activity, staff exposure and dose rate from patients

dc.contributor.authorParlak Y.
dc.contributor.authorGumuser G.
dc.contributor.authorSayit E.
dc.date.accessioned2025-04-10T11:10:30Z
dc.date.available2025-04-10T11:10:30Z
dc.date.issued2015
dc.description.abstractThe aim of this study was to determine the excretion of Samarium-153-ethylenediaminetetramethylphosphonic acid (153Sm- EDTMP) in urine and to calculate the dose rate of its retention in the body as a function of time and the dose received by the skin of laboratory staff 's finger. Urine samples were collected from 11 patients after intravenous injection of 153Sm-EDTMP. The measurements of dose rate were performed. Thermoluminescent dosemeters were used for absorbed dose measurements. Effective half-lives that were calculated from urine sample measurements were found as 7.1±3 h within the first 24 h. Whole body dose rates before collecting urine of patients were 60.0 ± 15.7 μSv h21 for within 1 h following 153Sm-EDTMP administration. The highest finger radiation dose is to the right-hand thumb (3.8 ± 2 mGy). The results of the study imply that patients who recieved 153Sm-EDTMP therapy should be kept a minumum of 8 h in an isolated room at hospital and that one staff should give therapy at most two patients per week. © The Author 2014.
dc.identifier.DOI-ID10.1093/rpd/ncu237
dc.identifier.urihttp://hdl.handle.net/20.500.14701/49229
dc.publisherOxford University Press
dc.titleSamarium-153 therapy for prostate cancer: The evaluation of urine activity, staff exposure and dose rate from patients
dc.typeArticle

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