English
| dc.contributor.author | Saribas, GS | |
| dc.contributor.author | Erdogan, D | |
| dc.contributor.author | Goktas, G | |
| dc.contributor.author | Akyol, SN | |
| dc.contributor.author | Hirfanoglu, IM | |
| dc.contributor.author | Gurgen, SG | |
| dc.contributor.author | Coskun, N | |
| dc.contributor.author | Ozogul, C | |
| dc.date.accessioned | 2024-07-18T11:55:35Z | |
| dc.date.available | 2024-07-18T11:55:35Z | |
| dc.description.abstract | TAYLOR & FRANCIS INC | |
| dc.identifier.issn | 1364-6893 | |
| dc.identifier.uri | http://akademikarsiv.cbu.edu.tr:4000/handle/123456789/6524 | |
| dc.language.iso | Article | |
| dc.publisher | 0144-3615 | |
| dc.subject | The aim of this study was to investigate the effects of cisplatin and the protective role of acetyl l-carnitine against uterine tube toxicity. Twenty-four female Wistar albino rats were divided into four groups: control group was injected with saline (control); group 2 was injected with acetyl l-carnitine; group 3 was injected with cisplatin; and group 4 was pre-treated with acetyl l-carnitine before cisplatin intraperitoneal injection. According to our results, a significant weight loss was observed in rats from group 3. The thickness of the wall and epithelium of uterine tube were decreased in group 3 rats. We elaborate the protein expression of caspase in epithelium and stroma by IHC. We found that the expression of caspase and the number of TUNEL-positive cells were increased in group 3 rats compared to the other groups. In our study, we showed the protective role of acetyl l-carnitine against uterine tube toxicity caused by cisplatin. | |
| dc.title | English | |
| dc.type | ANTIOXIDANT ENZYMES | |
| dc.type | RATS | |
| dc.type | DAMAGE | |
| dc.type | NEPHROTOXICITY | |
| dc.type | CHEMOTHERAPY | |
| dc.type | MECHANISMS | |
| dc.type | APOPTOSIS | |
| dc.type | ESTER | |
| dc.type | LIVER |