Association between uterine leiomyoma and fragmented QRS waves: a prospective case-control study

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dc.contributor.authorTatlici T.K.
dc.contributor.authorCetin N.
dc.contributor.authorKorpe B.
dc.contributor.authorKose C.
dc.contributor.authorKorkmaz V.
dc.date.accessioned2024-07-22T08:01:51Z
dc.date.available2024-07-22T08:01:51Z
dc.date.issued2024
dc.description.abstractOBJECTIVE: The aim of this study was to evaluate the relationship between uterine leiomyoma and fragmented QRS, a non-invasive indicator of cardiovascular risk and myocardial ischemia, in women with uterine leiomyoma. METHODS: In this prospective case-control study, a total of 47 patients diagnosed with uterine leiomyoma (case group) and 47 healthy individuals without uterine leiomyoma (control group) who had undergone bilateral tubal ligation surgery were included. Various demographic, clinical, and laboratory parameters and the presence of fragmented QRS were recorded. RESULTS: The leiomyoma group showed significantly higher body mass index (27.46±2.18 vs. 25.9±2.87 kg/m2, p=0.005) and waist circumference (91.34±9.30 vs. 84.97±9.3 cm, p=0.001) compared with the control group. Uterine volumes were also significantly higher in the leiomyoma group (235.75±323.48 vs. 53.24±12.81 mm3, p<0.001). The presence of fragmented QRS was detected in 18.1% of the patients. Multiple regression analysis identified age, fasting blood glucose value, and the presence of fragmented QRS as independent risk factors for the presence of leiomyoma. CONCLUSION: This study provides valuable insights into the relationship between uterine leiomyoma and fragmented QRS. The presence of fragmented QRS was identified as an independent risk factor for the presence of leiomyoma. Further research is needed to better understand the underlying mechanisms connecting uterine leiomyoma and cardiovascular health. © 2024 Associacao Medica Brasileira. All rights reserved.
dc.identifier.DOI-ID10.1590/1806-9282.20231359
dc.identifier.issn01044230
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/11608
dc.language.isoEnglish
dc.publisherAssociacao Medica Brasileira
dc.rightsAll Open Access; Gold Open Access
dc.subjectAdult
dc.subjectBody Mass Index
dc.subjectCase-Control Studies
dc.subjectElectrocardiography
dc.subjectFemale
dc.subjectHumans
dc.subjectLeiomyoma
dc.subjectMiddle Aged
dc.subjectMyocardial Ischemia
dc.subjectProspective Studies
dc.subjectRisk Factors
dc.subjectUterine Neoplasms
dc.subjectalanine aminotransferase
dc.subjectaspartate aminotransferase
dc.subjectcholesterol
dc.subjectcreatinine
dc.subjectestradiol
dc.subjectfollitropin
dc.subjectglucose
dc.subjecthemoglobin
dc.subjecthemoglobin A1c
dc.subjecthigh density lipoprotein cholesterol
dc.subjectinsulin
dc.subjectlow density lipoprotein cholesterol
dc.subjectluteinizing hormone
dc.subjecttriacylglycerol
dc.subjectvery low density lipoprotein cholesterol
dc.subjectabdominal circumference
dc.subjectadult
dc.subjectArticle
dc.subjectblood cell count
dc.subjectbody mass
dc.subjectcardiovascular risk
dc.subjectcase control study
dc.subjectcesarean section
dc.subjectclinical article
dc.subjectclinical trial
dc.subjectcohort analysis
dc.subjectcontrolled study
dc.subjectelectrocardiography
dc.subjectendometrial thickness
dc.subjectfemale
dc.subjectglucose blood level
dc.subjectheart muscle ischemia
dc.subjectheart rate
dc.subjecthematocrit
dc.subjecthomeostasis model assessment
dc.subjecthuman
dc.subjectleiomyoma
dc.subjectleukocyte count
dc.subjectparity
dc.subjectphysical examination
dc.subjectplatelet count
dc.subjectpregnancy
dc.subjectprospective study
dc.subjectQRS interval
dc.subjectrisk factor
dc.subjecturea nitrogen blood level
dc.subjectuterine tube ligation
dc.subjectuterus myoma
dc.subjectwaist circumference
dc.subjectcomplication
dc.subjectelectrocardiography
dc.subjectleiomyoma
dc.subjectmiddle aged
dc.subjectpathophysiology
dc.subjectprospective study
dc.subjectuterus tumor
dc.titleAssociation between uterine leiomyoma and fragmented QRS waves: a prospective case-control study
dc.typeArticle

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