The effect of an eight-week walking program on bone turnover markers and sRANKL/osteoprotegerin levels in post-menopausal women; [Sekiz haftalik yürüme programinin menopoz sonrasi kadinlarda kemik döngüsügöstergeleri ve sRANKL/osteoprotegerin düzeyleri üzerine etkisi]

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dc.contributor.authorBüyükyazi G.
dc.date.accessioned2024-07-22T08:21:56Z
dc.date.available2024-07-22T08:21:56Z
dc.date.issued2009
dc.description.abstractObjective: To examine the effect of an eight-week moderate intensity walking program on bone turnover markers, serum osteoprotegerin (OPG) and soluble receptor-activator of nuclear factor- kappa β ligand (sRANKL) in postmenopausal women. Material and Methods: Twelve postmenopausal women (45-62 years) completed an eight-week walking program at moderate intensity (60-65% maximum heart rate reserve). Non-walking women served as the control group (CG; n= 11). Body weight, percent body fat, body mass index (BMI), estimated maximal oxygen consumption (estimated VO2max), bone turnover markers, sRANKL, serum OPG and sRANKL/OPG ratio were measured before and after the intervention. Results: Eight-week walking program produced significant increases in VO 2max and reductions in body weight and BMI. Serum intact parathyroid hormone (iPTH), and β- crosslaps (CTx) reduced (p< 0.01, for both), sRANKL/OPG ratio (p< 0.01) and sRANKL values (p< 0.05) increased in the exercise group (EG). We detected significant reductions in the serum OPG levels of EG and CG (p< 0.01). No significant differences were observed between the changes in EG and CG in terms of bone turnover markers, OPG and sRANKL values. Conclusion: Eight-week moderate intensity walking program is beneficial for improving cardiorespiratory function in postmenopausal women to enable them to lead a less risky and a more independent life; however, it seems not so effective in changing the bone turnover markers and the OPG/sRANKL system. Copyright © 2009 by Türkiye Klinikleri.
dc.identifier.issn13000292
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/18850
dc.language.isoTurkish
dc.publisherTurkiye Klinikleri
dc.subjectalkaline phosphatase
dc.subjectosteoclast differentiation factor
dc.subjectosteoprotegerin
dc.subjectoxygen
dc.subjectparathyroid hormone
dc.subjectadult
dc.subjectalkaline phosphatase blood level
dc.subjectarticle
dc.subjectbody fat
dc.subjectbody mass
dc.subjectbody weight
dc.subjectbone turnover
dc.subjectcontrolled study
dc.subjectexercise intensity
dc.subjectfemale
dc.subjectheart rate
dc.subjecthuman
dc.subjecthuman experiment
dc.subjectnormal human
dc.subjectoxygen consumption
dc.subjectparathyroid hormone blood level
dc.subjectpostmenopause
dc.subjectprotein blood level
dc.subjectwalking
dc.titleThe effect of an eight-week walking program on bone turnover markers and sRANKL/osteoprotegerin levels in post-menopausal women; [Sekiz haftalik yürüme programinin menopoz sonrasi kadinlarda kemik döngüsügöstergeleri ve sRANKL/osteoprotegerin düzeyleri üzerine etkisi]
dc.typeArticle

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