Fluorescein dye disappearance test in patients with different degrees of epiphora

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dc.contributor.authorToprak, AB
dc.contributor.authorErkin, EF
dc.contributor.authorKayikçioglu, Ö
dc.contributor.authorSeymenoglu, G
dc.contributor.authorGüler, C
dc.contributor.authorUnlu, HH
dc.date.accessioned2024-07-18T11:47:01Z
dc.date.available2024-07-18T11:47:01Z
dc.description.abstractPURPOSE. To assess the diagnostic efficacy of a modification of the fluorescein dye disappearance test (DDT) in patients with different degrees of epiphora. METHODS. DDT was performed by instilling a drop of 2% fluorescein in the eye. Schirmer tear test strips were placed in the lower conjunctival fornix, after 3 and 10 minutes. The colour dilution on the strips was compared to a scale with known standards and the most closely comparable colour dilution was chosen and recorded as the visual scale test (VST) grade of the strip. The grey-scale value (GV) of each strip was calculated by computer image analysis. The control group comprised 44 patients, mean age 44.8 years (SD 7.5, range 30-60). There were 13 patients in group 1 with moderate epiphora; mean age was 44.2 years (SD 9.5, range 30-60). There were 17 patients in group 2 with severe epiphora; mean age was 48.3 years (SD 7.7, range 37-60). RESULTS. VST and GV differed significantly between controls and group 1 patients at 3 minutes (p=0.002, p=0.001), and between controls and group 2 patients at 3 minutes (p<0.001, p<0.001). There was no difference between groups 1 and 2 patients in VST and GV at 3 minutes. The differences were highly significant between controls and group 1 at 10 minutes (p=0.001, p=0.007), and between controls and group 2 at 10 minutes (p<0.001, p<0.001). The differences in GV and VST between groups 1 and 2 were significant at 10 minutes (p=0.026, p=0.018). CONCLUSIONS. This modified DDT permits identification of different degrees of epiphora in a non-invasive manner, it can therefore be used to evaluate the outcome of different treatment strategies.
dc.identifier.issn1120-6721
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/3186
dc.language.isoEnglish
dc.publisherWICHTIG EDITORE
dc.subjectLACRIMAL DRAINAGE FUNCTION
dc.subjectOCULAR IRRITATION
dc.subjectTEAR CLEARANCE
dc.subjectSCHIRMER TEST
dc.subjectSCINTIGRAPHY
dc.subjectOBSTRUCTION
dc.subjectDYNAMICS
dc.titleFluorescein dye disappearance test in patients with different degrees of epiphora
dc.typeArticle

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