English
| dc.contributor.author | Dogusal, G | |
| dc.contributor.author | Afacan, B | |
| dc.contributor.author | Bozkurt, E | |
| dc.contributor.author | Sönmez, I | |
| dc.date.accessioned | 2024-07-18T11:57:41Z | |
| dc.date.available | 2024-07-18T11:57:41Z | |
| dc.description.abstract | WILEY | |
| dc.identifier.issn | 1943-3670 | |
| dc.identifier.uri | http://akademikarsiv.cbu.edu.tr:4000/handle/123456789/7114 | |
| dc.language.iso | Article | |
| dc.publisher | 0022-3492 | |
| dc.subject | Background: This study aimed to evaluate the levels of resistin and tumor necrosis factor-alpha (TNF-alpha) in gingival crevicular fluid (GCF) and saliva of obese children with gingivitis. Methods: One-hundred and thirty children (65 obese and 65 normal weight; age range 8 to 12 years) were recruited for the study. The children were classified into four subgroups based on their body mass and periodontal status; 1) obese children with gingivitis (OG, n = 33); 2) obese children with healthy periodontium (OH, n = 32); 3) normal weight children with gingivitis (NWG, n = 32); 4) normal weight children with healthy periodontium (NWH, n = 33). Body mass index (BMI) percentile, probing pocket depth (PPD), gingival index (GI), and plaque index (PI) were recorded. Resistin and TNF-alpha were analyzed in GCF and saliva samples by ELISA. Results: (these children had higher BMI percentiles than normal weight children (p < 0.0001). PPD, GI, PI, GCF volume, GCF, and salivary resistin and TNF-alpha levels were similar between obese and normal weight children (P > 0.05). OG and NWG subgroups had significantly higher GI, PI, GCF volume, GCF resistin total amounts, and salivary resistin concentrations but lower GCF resistin and TNF-alpha concentrations than OH and NWH (P < 0.0001 for all). GCF resistin total amounts were positively correlated with GI, PI, and GCF TNF-alpha total amounts (P < 0.05). Conclusions: To our knowledge, this is the first study evaluated the levels of resistin in GCF and saliva of children. Obesity is not associated with GCF and salivary resistin and TNF-alpha levels in children in the presence of gingival inflammation. | |
| dc.title | English | |
| dc.type | PRO-INFLAMMATORY CYTOKINES | |
| dc.type | CHRONIC PERIODONTITIS | |
| dc.type | TNF-ALPHA | |
| dc.type | DENTAL-CARIES | |
| dc.type | SERUM-LEVELS | |
| dc.type | DISEASE | |
| dc.type | ADOLESCENTS | |
| dc.type | ASSOCIATION | |
| dc.type | OVERWEIGHT | |
| dc.type | WEIGHT |