Evaluation of patients with zygomycosis

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dc.contributor.authorOnur KAYA
dc.contributor.authorSema ÇAVUŞ ALP
dc.contributor.authorÖzge TURHAN
dc.contributor.authorMeltem TAŞBAKAN IŞIKGÖZ
dc.contributor.authorHüsnü PULLUKÇU
dc.contributor.authorMustafa Bülent ERTUĞRUL
dc.contributor.authorŞEBNEM ŞENOL AKAR
dc.contributor.authorÇiğdem Banu ÇETİN
dc.contributor.authorBetil BAYSAN ÖZHAK
dc.contributor.authorSELDA SAYIN KUTLU
dc.contributor.authorDilek Yeşim METİN
dc.contributor.authorMeltem AVCI
dc.contributor.authorGülşen MERMUT
dc.contributor.authorVildan OĞUZ AVKAN
dc.contributor.authorNur YAPAR
dc.date.accessioned2024-07-24T09:09:00Z
dc.date.available2024-07-24T09:09:00Z
dc.date.issued2014
dc.description.abstractAim: Zygomycosis is a severe angioinvasive infection caused by Zygomycetes. We retrospectively investigated 16 cases of zygomycosis. Materials and methods: The data of patients, who had been followed between 2004 and 2010 in 8 tertiary-care teaching hospitals, were reviewed. Demographic characteristics, underlying diseases, and clinical signs and symptoms of the patients, as well as diagnostic methods, data obtained by radiological imaging methods, and the therapies, were recorded. Therapeutic approaches, antifungal agents and duration of use, and the characteristics of the cases were identified. Results: The study included 11 female and 5 male subjects. The most common symptoms and clinical signs were fever (n = 9) and retroorbital pain (n = 7). Rhinocerebral zygomycosis was the most common form. The mean time elapsed for diagnosis was 14.26 ± 13.96 (range: 2 52) days. Antifungal therapy was given to 15 patients (94%). In addition to antifungal therapy, 12 patients underwent surgical intervention 1 to 4 times. The mean duration of receiving antifungal therapy was 61.4 ± 58.02 (range: 1 180) days. The median duration of treatment was 62.5 (range: 42 180) days in survivors. Conclusion: Zygomycosis is an infectious disease with high mortality despite antifungal therapy and surgical interventions.
dc.identifier.issn1300-0144
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/21761
dc.language.isoeng
dc.subject[Fen > Tıp > Cerrahi]
dc.titleEvaluation of patients with zygomycosis
dc.typeAraştırma Makalesi

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