COMET, TUNEL, and TEM analysis of an infertile male with short tail sperm

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dc.contributor.authorNurten DİKMEN
dc.contributor.authorAYŞEN DURMAZ GÜVEN
dc.contributor.authorAlper Bağrıyanık
dc.contributor.authorCumhur Gunduz
dc.contributor.authorErol Tavmergen
dc.contributor.authorSERAP CİLAKER MIÇILI
dc.contributor.authorHafize seda Vatansever
dc.contributor.authorEGE NAZAN TAVMERGEN GÖKER
dc.date.accessioned2025-04-14T05:50:12Z
dc.date.available2025-04-14T05:50:12Z
dc.date.issued2015
dc.description.abstractMale infertility is correlated with sperm morphology and sperm DNA damage, which are completely different from that of fertile individuals. Anaccurate sperm DNA damage analysis and ultrastructural examination of the ejaculate provide important support in the clinical evaluation. It issupposed that in the near future, the fertilization rate, pregnancy rate, and miscarriages could be predicted using the combination of these typesof tests in assisted reproductive technologies (ARTs). For this purpose, we report a very rare case of an infertile man having short tail sperm. Theinfertile man and his wife underwent in vitro fertilization (IVF) with intracytoplasmic sperm injection (ICSI). During this process, we examinedthe ultrastructure of the ejaculated sperm with transmission electron microscopy (TEM) and calculated the sperm DNA damage with terminaldeoxynucleotidyl transferase dUTP nick end labeling (TUNEL) and COMET assays. Then, we evaluated the association between sperm DNAdamage and embryo quality.
dc.identifier.e-issn1309-0380
dc.identifier.issn1309-0399
dc.identifier.urihttp://hdl.handle.net/20.500.14701/53685
dc.language.isoİngilizce
dc.subjectKadın Hastalıkları ve Doğum
dc.titleCOMET, TUNEL, and TEM analysis of an infertile male with short tail sperm
dc.typeOlgu Sunumu

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