Propolis prevents the effects of chronic alcohol intake on ocular tissues

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dc.contributor.authorEmre S.
dc.contributor.authorYilmaz Z.
dc.contributor.authorÖztürk F.
dc.contributor.authorEmre M.H.
dc.date.accessioned2024-07-22T08:21:37Z
dc.date.available2024-07-22T08:21:37Z
dc.date.issued2009
dc.description.abstractAim: This study is designed to investigate the protective effects of propolis in ocular tissues against chronic alcohol exposure. Material and Method: Wistar albino rats were used in this study. Rats were divided into 4 groups, and each group was fed a special liquid diet which contained an equal amount of calories. The control group was fed the liquid special diet without alcohol and propolis. We added propolis (150 mg/kg) to the diet of the second group. The diet of the third group contained alcohol, the concentration of which was increased progressively. The fourth group was fed a diet including propolis and alcohol. To counterbalance caloric intake, we decreased the amount of glucose in the special liquid diet for groups 3 and 4. At the end of 30 days, the animals were sacrificed and samples were kept at -80°C until evaluation. Specimens were investigated by light microscopy for morphology and morphometry. Results: In the histological investigation of ocular tissues, alcohol caused an increase in thickness of the cornea and corneal epithelium compared to the control group (p < 0.05). This incremental tendency was significantly reduced by propolis, and values were very close to those of the control group (p > 0.05). Alcohol did not cause any significant alteration of rat retinal thickness. Conclusion: This study showed that propolis is highly effective against corneal edema secondary to chronic alcohol intake. © 2009 S. Karger AG, Basel.
dc.identifier.DOI-ID10.1159/000229029
dc.identifier.issn00303747
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/18695
dc.language.isoEnglish
dc.subjectAlcoholism
dc.subjectAnimals
dc.subjectAnti-Infective Agents
dc.subjectCornea
dc.subjectCorneal Edema
dc.subjectHumans
dc.subjectPropolis
dc.subjectRats
dc.subjectRats, Wistar
dc.subjectRetina
dc.subjectalcohol
dc.subjectglucose
dc.subjectpropolis
dc.subjectalcohol consumption
dc.subjectanimal experiment
dc.subjectanimal tissue
dc.subjectarticle
dc.subjectcaloric intake
dc.subjectcontrolled study
dc.subjectcornea epithelium
dc.subjectcornea thickness
dc.subjectdiet supplementation
dc.subjecteye protection
dc.subjecthistology
dc.subjectmorphology
dc.subjectmorphometrics
dc.subjectnonhuman
dc.subjectpriority journal
dc.subjectrat
dc.subjectretina
dc.titlePropolis prevents the effects of chronic alcohol intake on ocular tissues
dc.typeArticle

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