The effects of eight-week walking programs of two different intensities on serum lipids and circulating markers of collagen remodelling in humans

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dc.contributor.authorBuyukyazi, G
dc.date.accessioned2024-07-18T11:39:47Z
dc.date.available2024-07-18T11:39:47Z
dc.description.abstractAim. - This study examined the effects of eight weeks of walking programs on serum lipids, circulation matrix metalloproteinase-9 (MMP-9) and tissue inhibitor of metal loproteinase-1 (TIMP-1). Methods. - Thirty-seven premenopausal women (30-55 years) completed eight weeks of walking programs either at moderate (similar to 5.25 +/- 0.28 km/h; similar to 53% maximum heart rate reserve (HRRmax) or high-intensity (similar to 7.33 +/- 0.24 km/h; similar to 73% HRRmax). Non-walking, sedentary women served as controls. Estimated Vo(2max) was assessed with a 2 km walking test; body composition was measured using body composition analyzer; lipid, MMP-9, and TIMP-1 concentrations were measured in serum. Results. - After eight weeks, estimated Vo(2max) improved in high-intensity walking group (HIWG; p < 0.01) and in moderate-intensity walking group (MIWG; p < 0.05); BMI, and percent body fat decreased (p < 0.05) in both exercise groups. Only HIW caused significant reductions in total cholesterol (TC), low-density lipoprotein-cholesterol (LDL-C), and MMP-9 levels (p<0.05); we found no significant changes in high-density lipoprotein-cholesterol and triglyceride levels in any of the groups. Exercise did not cause any significant changes in TIMP-1 levels apart from a nearly significant reduction in HIWG (p = 0.084). Conclusion. - Walking programs with different intensity bring about favorable changes; but significant improvements for protective effects against cardiovascular diseases may be attained only with high-intensity walking programs due to the reduction in TC, LDL-C and MMP-9 levels. (C) 2008 Elsevier Masson SAS. All rights reserved.
dc.identifier.issn0765-1597
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/1877
dc.language.isoEnglish
dc.publisherELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
dc.subjectCORONARY-ARTERY DISEASE
dc.subjectC-REACTIVE PROTEIN
dc.subjectMATRIX METALLOPROTEINASES
dc.subjectSKELETAL-MUSCLE
dc.subjectMYOCARDIAL-INFARCTION
dc.subjectHYPERTENSIVE PATIENTS
dc.subjectTISSUE INHIBITORS
dc.subjectPHYSICAL-FITNESS
dc.subjectOLDER MEN
dc.subjectEXERCISE
dc.titleThe effects of eight-week walking programs of two different intensities on serum lipids and circulating markers of collagen remodelling in humans
dc.typeArticle

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