Where does current and future pediatric asthma treatment stand? Remodeling and inflammation: Bird's eye view

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dc.contributor.authorYilmaz, O
dc.contributor.authorYuksel, H
dc.date.accessioned2024-07-18T11:48:46Z
dc.date.available2024-07-18T11:48:46Z
dc.description.abstractAirway remodeling is the chronic outcome of inflammation in asthma and a point of intervention between pediatric and adult ages. Pediatric asthma has been of great interest in the efforts to find a valuable time to interrupt remodeling. Various experimental and clinical research have assessed the effect of current therapeutic modalities on airway remodeling in asthma and many new agents are being developed with promising results. The heterogeneity in the results of these studies may lie in the heterogeneity of pathogenesis leading to asthma and remodeling; underlying the need for individualized treatment of the unique pathogenetic characteristics of each child's asthma. The aim of this review is to summarize the evidence about the influence of current and future therapeutic modalities in the concept of inflammation and remodeling in pediatric asthma. Pediatr Pulmonol. 2016;51:1422-1429. (c) 2016 Wiley Periodicals, Inc.
dc.identifier.issn8755-6863
dc.identifier.other1099-0496
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/3488
dc.language.isoEnglish
dc.publisherWILEY-BLACKWELL
dc.subjectBRONCHIAL EPITHELIAL-CELLS
dc.subjectSEVERE PERSISTENT ASTHMA
dc.subjectSMOOTH-MUSCLE-CELLS
dc.subjectTO-MODERATE ASTHMA
dc.subjectCHILDHOOD ASTHMA
dc.subjectVITAMIN-D
dc.subjectAIRWAY INFLAMMATION
dc.subjectCYSLT(1) RECEPTOR
dc.subjectMURINE MODEL
dc.subjectCHILDREN
dc.titleWhere does current and future pediatric asthma treatment stand? Remodeling and inflammation: Bird's eye view
dc.typeReview

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