Assessment of neuromuscular and haemodynamic effects of cisatracurium and vecuronium under sevoflurane-remifentanil anaesthesia in elderly patients

Simple item page
dc.contributor.authorKeles, GT
dc.contributor.authorYentür, A
dc.contributor.authorÇavus, Z
dc.contributor.authorSakarya, M
dc.date.accessioned2024-07-18T11:49:18Z
dc.date.available2024-07-18T11:49:18Z
dc.description.abstractBackground and objective: Neuromuscular block times, quality of muscle relaxation for tracheal tube insertion, and the haemodynamic effects after cisatracurium and vecuronium under sevoflurane-remifentanil anaesthesia were compared in elderly patients. Methods: The study was performed in 40 patients over 65 yr of age. Anaesthesia was induced with thiopental, and maintained with sevoflurane in N2O/O-2 and remifentanil. Cisatracurium 0.15 mg kg(-1) or vecuronium 0.1 mg kg(-1) were administered after induction. Intubation was attempted when neuromuscular block was 95%. Onset time, clinical duration of action, recovery index, spontaneous recovery time and tracheal intubation conditions were assessed. Haemodynamic parameters were also monitored. Results: The average ages of the patients were 72.5 +/- 5.1 and 73.6 +/- 6.3 in the cisatracurium and vecuronium groups, respectively. Onset time was significantly shorter after vecuronium, 158 +/- 34 s vs. 200 +/- 50 s, respectively. Recovery index was significantly shorter after cisatracurium, 19.5 +/- 7.5 s vs. 33.7 +/- 18.6 s (P < 0.05). Clinical duration and spontaneous recovery time were similar in both groups as well as haemodynamic variables. Conclusions: In elderly patients, vecuronium has a faster onset time while cisatracurium has a shorter recovery index under sevoflurane-remifentanil anaesthesia.
dc.identifier.issn0265-0215
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/3924
dc.language.isoEnglish
dc.publisherGREENWICH MEDICAL MEDIA LTD
dc.subjectD-TUBOCURARINE
dc.subjectPHARMACODYNAMICS
dc.subjectPHARMACOKINETICS
dc.subjectATRACURIUM
dc.subjectBLOCK
dc.subjectPANCURONIUM
dc.subjectISOFLURANE
dc.subjectHALOTHANE
dc.subjectDURATION
dc.subjectINFUSION
dc.titleAssessment of neuromuscular and haemodynamic effects of cisatracurium and vecuronium under sevoflurane-remifentanil anaesthesia in elderly patients
dc.typeArticle

Files

Collections

Web of Science Koleksiyonu