Extended spectrum beta-lactamase production and susceptibility to antibiotics in Escherichia coli strains isolated from community acquired and nosocomial infections; [Toplum kökenli̇ ve nozokomi̇yal i̇drar yolu enfeksi̇yonlarindan i̇zole edi̇len Escherichia coli suşlarinda geni̇şlemi̇ş spektrumlu beta-laktamaz varliǧinin araştirilmasi ve çeşi̇tli̇ anti̇bi̇yoti̇klere duyarliliklari]
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2001
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Abstract
This study was planned to determine the extended spectrum beta-Lactamase (ESBL) production and antibiotic susceptibility of Escherichia coli strains isolated from patients with nosocomial and community acquired urinary tract infections. A total of 218 E. coli strains isolated from 126 community acquired and 92 nosocomial urinary tract infections were included to the study and ESBL production was investigated by double disk synergy method. ESBL positivity rates of isolates from patients with community acquired and nosocomial urinary tract infections were found to be as 3.9% and 9.8%, respectively (p<0.05). Susceptibility to amikacin, amoxicillin/clavulanate, aztreonam, gentamicin, imipenem, netilmicin, ofloxacin, piperacillin, cephalotin, cefepime, ceftazidime, ceftriaxone, cefuroxime, ciprofloxacin, trimethoprim/sulfamethoxazole was investigated by disk diffusion method, and although the resistance rates to these antimicrobials were found higher in nosocomial strains than those community strains, the differences were statistically insignificant, except for gentamicin.