Synthesis of Cycloalk[b]indole Bearing Spiropiperidine Derivatives

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dc.contributor.authorHizliateş C.G.
dc.contributor.authorGülle S.
dc.contributor.authorErgün Y.
dc.date.accessioned2024-07-22T08:12:19Z
dc.date.available2024-07-22T08:12:19Z
dc.date.issued2016
dc.description.abstract(Chemical Equation Presented) The novel heterocyclic compounds that have cycloalk[b]indole moiety bearing spiropiperidinone and spiropiperidinedione (3a, 3b, 3c, 5a, 5b, 8a, 8b, and 10a) were synthesized for the first time. The synthesis of spiropiperidinone and spiropiperidinedione structures was performed by a new method. These compounds are similar to sedative and hypnotic drugs such as methyprylon, glutethimide, and thalidomide. © 2015 HeteroCorporation.
dc.identifier.DOI-ID10.1002/jhet.2395
dc.identifier.issn0022152X
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/15996
dc.language.isoEnglish
dc.publisherHeteroCorporation
dc.subject4 methyl 1h spiro[cyclopenta[b]indole 2,3' piperidine] 1,2'(3h,4h)dione
dc.subject4 methyl 1h spiro[cyclopenta[b]indole 2,3' piperidine] 1,2',6' (3h,4h)trione
dc.subject4 methyl 1h spiro[cyclopenta[b]indole 2,3' piperidine] 2',3 (4h)dione
dc.subject4 methyl 1h spiro[cyclopenta[b]indole- 2,3' piperidine] 2',3,6' (4h)trione
dc.subject5 methyl 7,8 dihydro 5h spiro[cyclohepta[b]indole 9,3' piperidine] 2',6',10(6h)trione
dc.subject9 methyl 1,2 dihydrospiro[carbazole 3,3' piperidine] 2',4 (9h)dione
dc.subject9 methyl 1,2 dihydrospiro[carbazole 3,3' piperidine] 2',4,6' (9h)trione
dc.subject9,9' dimethyl 3, 4, 3', 4', di dihydrospiro[bicarbazole 2,3',2',3''dipiperidine] 1,2',6',1',2'',6''(9h,9'h)hexaone
dc.subjectcycloalk[b]indole derivative
dc.subjectglutethimide
dc.subjectheterocyclic compound
dc.subjectindole derivative
dc.subjectmethyl 2 (2 cyanoethyl) 4 methyl 1 oxo 1,2,3,4 tetrahydrocyclopenta[b]indole 2 carboxylate
dc.subjectmethyl 3 (2 cyanoethyl) 9 methyl 4 oxo 2,3,4,9 tetrahydro 1h carbazole 3 carboxylate
dc.subjectmethyl 4 methyl 1 oxo 1,2,3,4 tetrahydrocyclopenta[b]indole 2 carboxylate
dc.subjectmethyl 5 methyl 10 oxo 5,6,7,8,9,10 hexahydrocyclohepta[b]indole 9 carboxylate
dc.subjectmethyl 5 methyl 6 oxo 5,6,7,8,9,10 hexahydrocyclohepta[b]indole 7 carboxylate
dc.subjectmethyl 7 (2 cyanoethyl) 5 methyl 6 oxo 5,6,7,8,9,10 hexahydrocyclohepta[b]indole 7 carboxylate
dc.subjectmethyl 9 (2 cyanoethyl) 5 methyl 10 oxo 5,6,7,8,9,10 hexahydrocyclohepta[b]indole 9 carboxylate
dc.subjectmethyl 9 methyl 4 oxo 2,3,4,9 tetrahydro 1h carbazole 3 carboxylate
dc.subjectmethyprylon
dc.subjectpiperidine derivative
dc.subjectspiropiperidine derivative
dc.subjectspiropiperidinedione derivative
dc.subjectthalidomide
dc.subjectunclassified drug
dc.subjectanalytic method
dc.subjectArticle
dc.subjectbiological activity
dc.subjectchemical analysis
dc.subjectchemical reaction
dc.subjectdrug structure
dc.subjectdrug synthesis
dc.subjectpolymerization
dc.subjectstructure analysis
dc.titleSynthesis of Cycloalk[b]indole Bearing Spiropiperidine Derivatives
dc.typeArticle

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